Publications by authors named "Kamal Hasani"
The carbapenem-resistant (CRE) pose a pressing public health concern. Here, we investigated the frequency of CRE bacteria, carbapenemase-encoding genes, and the molecular epidemiology of carbapenemase-resistant in wastewater resources and healthy carriers in Iran. Out of 617 bacteria, 24% were carbapenem-resistant.
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- Beta-lactamase-producing Enterobacterales bacteria are causing increasingly severe infections, spreading outside hospitals, and posing a global health threat.
- A study in Ardabil, Iran, examined wastewater from livestock and poultry slaughterhouses, identifying 80 Enterobacterales isolates, primarily from Escherichia coli and Citrobacter spp.
- Among these, 18.7% were ESBL producers and 2.5% were AmpC producers, with all isolates being multidrug-resistant, raising concerns for zoonotic transmission to humans through contaminated food and the environment.
Article Synopsis
- * Out of 146 isolates, 8.9% were ESBL-producers and 15.75% were AmpC-producers, with common resistant strains identified across all sections of the wastewater facility, particularly in effluent samples.
- * A significant number of these isolates showed multi-drug resistance, with the highest resistance rates against ampicillin, nalidixic acid, and cephalexin, raising concerns about antibiotic resistance in treated waste.