Anxiety in major depression and cerebrospinal fluid free gamma-aminobutyric acid.

Background: Low gamma-aminobutyric acid (GABA) is implicated in both anxiety and depression pathophysiology. They are often comorbid, but most clinical studies have not examined these relationships separately. We investigated the relationship of cerebrospinal fluid (CSF) free GABA to the anxiety and depression components of a major depressive episode (MDE) and to monoamine systems.

Ministers' perceptions of church-based programs to provide depression care for African Americans.

African Americans, compared with white Americans, underutilize mental health services for major depressive disorder. Church-based programs are effective in reducing racial disparities in health; however, the literature on church-based programs for depression is limited. The purpose of this study was to explore ministers' perceptions about depression and the feasibility of utilizing the church to implement evidence-based assessments and psychotherapy for depression.

Psychological pathways from childhood sexual and physical abuse to HIV/sexually transmitted infection outcomes among homeless women: the role of posttraumatic stress disorder and borderline personality disorder symptoms.

This study examines the psychological factors linking childhood abuse and HIV/sexually transmitted infection outcomes among 190 single homeless women in New York City. Participants were assessed for mental health symptoms, sexually transmitted infections, and exposure to childhood sexual and physical abuse. Findings indicate that the relationship between childhood abuse and HIV/sexually transmitted infection diagnoses during adulthood is mediated by a combination of posttraumatic stress disorder and borderline personality disorder symptoms.

Factors Associated with Anxiety and Depression among African American and White Women.

Background. We examined factors associated with depression and anxiety in a cohort of low-income Baltimore women. Methods.