Resistance development in pink bollworm (Pectinophora Gossypiella Saunders) against Bt cotton and its' establishment as mid season pest in India.

The pink boll worm now became a menace for sustainable cultivation of Bt cotton in India. Based on the data recorded in unsprayed conditions at 13 different locations of north, central and south cotton growing zone between 2007 and 2023, initiation of green boll damage during later part of the season was observed on Bt cotton genotype during 2009-2014 wherein incidence of PBW already existed on non-Bt genotype. In our research, between 2014 and 2017, the central and southern regions of India experienced a rise in the survival of pink bollworms on Bt cotton surpassing the Economic Threshold Level (ETL) whereas in the north zone PBW incidence started in 2018 at experimental locations.

Staphylococcus hemolyticus: The Most Common and Resistant Coagulase-Negative Staphylococcus Species Causing Bacteremia in North India.

Introduction: Coagulase-negative (CoNS) species are normal skin commensals but may also cause bacteremia. Therefore, isolating a CoNS species on blood culture often leads to a diagnostic dilemma about whether to consider the isolate as a true pathogen or not. This study was done to understand the distribution of various CoNS species in bloodstream infections, determine their antibiotic resistance patterns, and identify possible risk factors and patient outcomes in hospital settings.

An alarming surge of scrub typhus cases presenting as acute encephalitis in children.

Scrub typhus, which is prevalent in the Asia Pacific region is most feared owing to its life-threatening neurological complications. We present four cases of scrub typhus with acute encephalitis, including one with multiorgan failure and another serologically proven co-infection with Hepatitis C. Treatment of scrub typhus is not, however, so difficult, so its early diagnosis is paramount.

Seroprevalence of Brucellosis in Patients Having Complained of Joint Pain: A Case Control.

Background: Brucellosis is a neglected zoonotic disease affecting humans and animals.

Objectives: This study aimed to estimate the seroprevalence of brucellosis in patients with joint pain.

Methods: A total of 200 participants aged from 7 to 86 years were involved in this study.

Molecular Characterization of Extended Spectrum β-Lactamase Producing and Isolates and Their Antibiotic Resistance Profile in Health Care-Associated Urinary Tract Infections in North India.

 Healthcare-associated urinary tract infections (HAUTIs) caused by gram-negative pathogens have emerged as a global concern. So far, little is known about the epidemiology of extended-spectrum β lactamase (ESBL)-producing and in HAUTIs in India. The study was carried to determine the antibiotic resistance pattern and ESBL-producing genes in and strains isolated from HAUTIs in a tertiary institute in North India.

Outcomes in Oxacillinases β-Lactamases (OXA-48) and New Delhi Metallo-β-Lactamase (NDM-1)-Producing, Carbapenem-Resistant Klebsiella Pneumoniae Isolates Obtained From Bloodstream Infections.

Background: Carbapenemase-producing (CRKP) has become a menace in several intensive care units, which needs to be controlled immediately after being reported by a laboratory. Detection in the laboratory is usually done using phenotypic methods and it is not known whether knowledge of these genes helps in individual patient management. This study aimed to compare the outcomes of oxacillinases β-lactamases (OXA-48) and New Delhi metallo-β-lactamase (NDM-1)-producing CRKP isolates, the two most common carbapenemases reported from India, obtained from patients with bloodstream infections in an ICU in a tertiary care center in North India and to compare the different laboratory methods for their detection.

Scrub Typhus and its co-infection with Leptospirosis at a tertiary care hospital in Uttar Pradesh.

The diagnosis of Scrub Typhus is now improving with the availability of an array of serological tests at the majority of diagnostic centres and of molecular tests at advanced laboratories. Our study focuses on evaluating the spectrum of Scrub Typhus and its coinfection with Leptospirosis in patients presenting with acute febrile illness. A total of 1743 blood samples were collected from both In and Out Patient Department (OPD) patients and analyzed for anti and anti- IgM antibodies.

Serological and molecular study of Leptospira in pediatric patients at a tertiary care centre of northern India.

Leptospirosis is considered as one of the most neglected zoonotic tropical diseases. Animals and humans acquire this infection through direct contact with contaminated urine or body fluids of infected animals. This prospective study was undertaken to know the proportion of leptospirosis in pediatric patients presented with acute febrile illness at the Post Graduate Department of Microbiology, King George's Medical University, Lucknow, Uttar Pradesh.

Prediction Rule for Scrub Typhus Meningoencephalitis in Children: Emerging Disease in North India.

Objectives: To evaluate the proportion of scrub typhus meningoencephalitis among children with acute encephalitis syndrome and to outline its differentiating features. To develop a prediction rule for scrub typhus meningoencephalitis.

Methods: A prospective cohort study was conducted at a tertiary care public hospital in Northern India.

Prevalence of reproductive tract infections in women attending a tertiary care center in Northern India with special focus on associated risk factors.

Background: Reproductive tract infections (RTIs) continue to present major health, social, and economic problems worldwide, and their complications are the most important causes of morbidity and mortality for women, especially in developing countries. Interest in RTIs and their management has increased tremendously because the presence of a RTI in the sexual partner increases the risk of acquisition of HIV.

Aims: The aim of this study is to know the prevalence of RTIs, its correlation with clinical features and associated risk factors in women of reproductive age group attending a tertiary care center in Lucknow.

Surgical versus non-surgical interventions in people with adolescent idiopathic scoliosis.

Background: Adolescent idiopathic scoliosis (AIS) is a three-dimensional deformity of the spine. While AIS can progress during growth and cause a surface deformity, it is usually not symptomatic. However, if the final spinal curvature surpasses a certain critical threshold, the risk of health problems and curve progression is increased.

High-level aminoglycoside resistance and beta-lactamase production in enterococci at a tertiary care hospital in India.

Enterococci, a family of important opportunistic pathogens, exhibits intrinsic resistance to a number of antimicrobial agents in addition to acquired multidrug resistance. The present study was conducted to determine whether enterococci at a tertiary care hospital in India exhibit high-level aminoglycoside resistance and beta-lactamase production. Enterococci were isolated from various clinical specimens and identified phenotypically.