Effective Antimalarial Activities of α-Hydroxy Diynes Isolated from Ongokea gore.

Three diynes, octadec-17-ene-9,11-diynoate ethyl (1: ), 8-hydroxy-octadeca-13,17-diene-9,11-diynoate ethyl (2: ), and 8-hydroxy-octadec-13-ene-9,11-diynoate ethyl (3: ), were isolated from seed oil. The structure assignment of these three compounds was based according to chemical and spectroscopic data. They were screened against , the parasite that causes malaria.

Antisickling activity of butyl stearate isolated from Ocimum basilicum (Lamiaceae).

Objective: To perform phytochemical analyses on the leaves of Ocimum basilicum L. (O. basilicum), to elucidate the structure of isolate and then perform the antisickling activity on the crude extract and on the isolate.