Publications by authors named "Kalra V"

Domain-specific vocabulary, which is crucial in fields such as Information Retrieval and Natural Language Processing, requires continuous updates to remain effective. Incremental Learning, unlike conventional methods, updates existing knowledge without retraining from scratch. This paper presents an incremental learning algorithm for updating domain-specific vocabularies.

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Lithium-sulfur batteries are limited by the high mobility of polysulfides in the electrolyte, which allows them to migrate from the cathode to the lithium anode. This is known as polysulfide shuttling and simultaneously diminishes the active material and poisons the anode. Various cathode additives have been shown empirically to mitigate this problem, although the mechanism is not often ascertained experimentally.

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The eyes play a crucial role in vision and emotional expression, and their loss can profoundly affect appearance and psychological well-being. Eye loss may result from trauma, tumors, infections, malignancies, or congenital abnormalities. Surgical methods for removing an eye include enucleation, evisceration, and exenteration.

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Article Synopsis
  • The study aimed to identify the types of bacteria causing acute otitis externa (AOE) and their antimicrobial sensitivities in patients from a tertiary care center in North India.
  • Out of 66 patients, 50 samples tested positive for bacterial cultures, with gram-negative bacteria accounting for 60% and gram-positive for 40%, the most common being Pseudomonas aeruginosa (48%).
  • The findings emphasized the importance of regularly assessing bacterial flora and antimicrobial resistance to ensure effective treatment for AOE, as bacteria showed varying susceptibilities to different antibiotics.
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The high theoretical energy density of metal-sulfur batteries compared to their lithium-ion counter parts renders sulfur-based electrode chemistries attractive. Additionally, sulfur is relatively abundant and environmentally benign. Yet, issues like the low conductivity of sulfur, polysulfide (PS) formation, and shuttling have hindered the development of sulfur chemistries.

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Objective: Mild traumatic brain injury (mTBI) can impair executive function, learning, and memory, which can negatively impact driving ability. However, little is known how the driving performance of young drivers may be impacted acutely after mTBI. This study aimed to evaluate simulated driving within 96 h of mTBI among young drivers as compared to matched healthy controls, and assess the effects of increased cognitive load on driving performance.

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Background: Isolated frontal sinus involvement in mucormycosis is seen very infrequently. Recent technological advances including image guided navigation and angled endoscopes have shifted paradigm towards minimally invasive surgeries. Open approaches are still relevant for the disease of frontal sinus with lateral extension where effective clearance cannot be obtained if approached endoscopically.

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Lipomas are slow growing tumors rarely found in children. We report a very rare case of an intermuscular fibrolipoma found deep within the posterior triangle of the neck. A 3 year old child was brought with the complaints of right sided neck mass and an inability to fully turn his head for two months.

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Article Synopsis
  • Recent advancements in lithium-sulfur (Li-S) batteries have focused on addressing polysulfide shuttling, though existing solutions often use volatile ether electrolytes.
  • Researchers have developed a stable monoclinic γ-sulfur phase within carbon nanofibers, enabling Li-S battery operation in less volatile carbonate electrolytes for up to 4000 cycles.
  • This study is the first to successfully synthesize stable γ-sulfur and demonstrates a unique redox mechanism that prevents polysulfide formation, potentially paving the way for new research in Li-S battery technologies.
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To analyse the patients with foreign body oesophagus in relation to the clinico-radiological and socio-economic profile. The present prospective study was conducted on 100 consecutive patients of all age groups who underwent oesophagoscopy for suspected foreign body ingestion in a tertiary care hospital. The most common age group affected was 0-5 years.

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COVID-19 detection currently relies on testing by reverse transcription polymerase chain reaction (RT-PCR) or antigen testing. However, SARS-CoV-2 is expected to cause significant metabolic changes in infected subjects due to both metabolic requirements for rapid viral replication and host immune responses. Analysis of volatile organic compounds (VOCs) from human breath can detect these metabolic changes and is therefore an alternative to RT-PCR or antigen assays.

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Hypertrophic cardiomyopathy (HCM) is a common but an underdiagnosed condition. Fasciculoventricular bypass tract (FVBT) is rare. Concomitant presence of both conditions is well described in Danon disease.

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Objective: To evaluate the short-term outcomes of non-vigorous infants born through meconium-stained amniotic fluid (MSAF) before and after implementation of no-tracheal suctioning guidelines.

Study Design: Single-center retrospective study of ≥36-week gestation neonates with MSAF.

Results: During routine-suction era (9/2013-12/2014), 280/2306 neonates (12%) were born through MSAF and 39 (14%) were non-vigorous.

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Brain, a subtle organ of multifarious nature presents plethora of physiological, metabolic and bio-chemical convolutions that impede the delivery of biomolecules and thereby resulting in truncated therapeutic outcome in pathological conditions of central nervous system (CNS). The absolute bottleneck in the therapeutic management of such devastating CNS ailments is the BBB. Another pitfall is the lack of efficient technological platforms (due to high cost and low approval rates) as well as limited clinical trials (due to failures of neuro‑leads in late-stage pipelines) for CNS disorders which has become a literal brain drain with poorest success rates compared to other therapeutic areas, owing to time consuming processes, tremendous convolutions and conceivable adverse effects.

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Purpose: An extensive literature has postulated multiple etiologies for aqueductal stenosis. No publications were found, discussing that evolutionary modifications might explain aqueductal anomalies. This study's objectives were to review the evolutionary modifications of vertebrates' tectum structures that might explain human aqueduct anomalies.

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Background: Described to be antithrombotic and antihypertensive, nattokinase is consumed for putative cardiovascular benefit. However, no large-scale, long-term cardiovascular study has been conducted with nattokinase supplementation.

Objective: To determine the effect of nattokinase on subclinical atherosclerosis progression and atherothrombotic biomarkers.

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Oxidative chemical vapor deposition (oCVD) offers unique advantages as a liquid-free processing technique in synthesizing and integrating conducting polymers, including polyaniline (PANI), by enabling conformal coatings onto nanostructured substrates, like carbon nanofibers. With relatively thick nanofiber mats, the challenge is to ensure uniform coating thickness through the porous substrates. Here, the substrate temperature during oCVD is found to be a primary factor influencing PANI coating uniformity.

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Seventy one patients (43 children and 28 adults) of thyroglossal duct remnants (TGDRs) presented at a tertiary care institute from January 2001 to September 2017 were retrospectively analysed. The mean age of presentation was 7.15 years in children and 26.

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Bio-molecules are the most important target to be considered while designing any drug delivery system. The logic lies in using such bio-sensing or bio-mimicking systems in their formulations that can mimic the active site of those receptors to which the drug is going to bind. Polymers mimicking the active site of target enzymes are regarded as bio-inspired polymers and can be used to ameliorate many diseased conditions.

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eIF4A is a RNA-stimulated ATPase and helicase. Besides its key role in regulating cap-dependent translation initiation in eukaryotes, it also performs specific functions in regulating cell cycle progression, plant growth and abiotic stress tolerance. Flowering plants encode three eIF4A paralogues, eIF4A1, eIF4A2 and eIF4A3 that share conserved sequence motifs but differ in functions.

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Foreign body ingestion is common in infants and children, but they can pose a difficult situation and a diagnostic problem if the foreign body is embedded in the soft tissues of the pharynx. To the best of our knowledge, this is the first case reported with such an unusually shaped foreign body having three sharp ends embedded at two different locations in the hypopharynx of a kid such small in age giving rise to respiratory as well as feeding problem. Secondly, a sharp foreign body penetrating arytenoid causing its swelling and inflammation, thus compromising the glottic opening and producing stridor is a rare phenomenon.

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