Surgeons' opinions and concerns regarding prophylactic mesh placement when conducting a permanent ileo- and colostomy A survey among 172 surgeons in Germany, Switzerland, and Austria.

Background: Prophylactic mesh placement when creating a permanent colostomy was recommended by the 2017 European Hernia Society guidelines on the prevention and treatment of parastomal hernias (GPTPH2017). The extent of this recommendation is under debate based on the long-term data from clinical trials. Our aim was to conduct a survey of surgeons revealing perspectives and concerns regarding GPTPH2017 and to discuss their concerns.

HeRO graft-The results of the cologne single center study.

Objective: The HeRO graft is a technique for vascular access in patients with limited treatment options; however, the published results with the HeRO graft are diverging. We therefore conducted a single-center study.

Methods: Patient records between July 2014 and February 2020 from Vascular Access Unit of the Department of Vascular and Endovascular Surgery of University Clinic of Cologne (Germany) were reviewed.

[Reconstruction of caval veins].

Objective: To study the possibilities and results of reconstruction of caval veins.

Material And Methods: We analyzed the results of reconstruction of caval veins in 31 patients (19 men and 12 women) including superior vena cava (SVC) in 5 cases and inferior vena cava (IVC) in 26 cases. Penetrating wounds with vascular damage were found in 8 patients.

[Endoleaks in endovacular infrarenal abdominal aortic aneurysm repair. (Part II)].

Searching for literature data was performed in the PubMed, Scopus and eLIBRARY databases. In the second part, we considered modern classifications of endoleaks type 3, 4 and 5 after endovascular infrarenal abdominal aortic aneurysm repair, etiology, risk factors, classification of endoleaks. Modern data on effectiveness of their treatment by various methods are presented.

Late Endograft Migration After Thoracic Endovascular Aortic Repair: A Systematic Review and Meta-analysis.

Purpose: The objective of this systematic review was to report the cumulative incidence of endograft migration (EM), as well as the morbidity, reintervention rates, and mortality related to EM. This study aimed to provide evidence-based data on patient-relevant sequelae of EM after thoracic endovascular aortic repair (TEVAR) performed using contemporary aortic endografts.

Materials And Methods: A systematic electronic search of literature in MEDLINE (via PubMed), Web of Science, and Cochrane Central Register of Controlled Trials was performed.

[Endoleaks in endovacular treatment of infrareneral abdominal aortic aneurysm (part I)].

We analyzed the PubMed, Scopus databases and the eLIBRARY electronic library regarding appropriate literature data. In the first part, modern classifications of endoleaks type 1 and 2 after stenting of infrarenal aortic aneurysm are considered. We described causes, risk factors and effectiveness of various treatment options.

EVAR as a treatment option for high-risk nonagenarians with complicated abdominal aortic aneurysms.

Abdominal aortic aneurysm (AAA) is a life-threatening disease, with an extremely high risk of death when ruptured. With the increase in life expectancy AAA is becoming more prevalent in aging patients. Elective and emergency procedures in elderly patients with AAA are becoming more common, but the indications for aortic repair and outcomes in geriatric patients are debatable.

Novel external stenting for reconstruction of high flow arteriovenous fistula.

Background: High-flow arteriovenous fistulae (HF-AVF) may lead to adverse cardiac remodeling in hemodialysis patients. We have investigated whether a novel external stent is safe and effective in reducing and stabilizing flow rates during a 1-year follow-up after HF-AVF reconstruction.

Methods: All patients with HF-AVF (access flow rate ⩾ 1500 ml/min), who underwent HF-AVF reconstruction with external stenting in two centers between June 2018 and May 2020, were included in this retrospective analysis.

[Some aspects of iatrogenic vessel injury].

Iatrogenic events made up 1-10% of in-hospital mortality. Currently, iatrogenic vascular injuries are described for almost all surgical areas. Incidence of iatrogenic vascular injuries is gradually increased that is primarily associated with high number of percutaneous endovascular interventions.

Patient and family experience with transthyretin amyloid cardiomyopathy (ATTR-CM) and polyneuropathy (ATTR-PN) amyloidosis: results of two focus groups.

Background: Transthyretin amyloidosis, or ATTR, is a progressive and debilitating rare proteopathy generally manifested as either transthyretin amyloid polyneuropathy (ATTR-PN) or transthyretin amyloid cardiomyopathy (ATTR-CM). Irrespective of the clinical presentation, affected patients manage a chronic and life-threatening condition that severely impacts their quality of life. Although the primary symptoms and diagnostic criteria for ATTR are increasingly being discussed in the medical literature, due in large part by continual advances in uncovering disease pathophysiology, there exists a surprising paucity of published data on the patient journey and family experience.

ElectroSens Platform with a Polyelectrolyte-Based Carbon Fiber Sensor for Point-of-Care Analysis of Zn in Blood and Urine.

In this paper, we describe an electrochemical sensing platform-ElectroSens-for the detection of Zn based on self-assembled polyelectrolyte multilayers on the carbon fiber (CF) electrode surface. The CF-extended surface facilitates the usage of a small volume electrochemical cell (1 mL) without stirring. This approach allows making a low-cost three-electrode platform.

[Review of the proceedings of the 68th International Congress of the European Society of Cardiovascular and Endovascular Surgery (May 22-25, 2019)].

This article covers the main trends of the work of the 68th International Congress of the European Society of Cardiovascular and Endovascular Surgery, reviewing the papers encompassing current problems in not only vascular but also cardiac surgery.

A Novel Inside-out Access Approach for Hemodialysis Catheter Placement in Patients With Thoracic Central Venous Occlusion.

Rationale & Objective: Left-sided internal jugular and all subclavian central venous catheters (CVCs) cause thoracic central vein occlusions (TCVOs) more often than right-sided internal jugular catheters. To enable right-sided CVC placement in patients with TCVO, an inside-out access (IOA) approach was established at 3 vascular access centers in Europe involving use of a novel IOA device advanced from the right femoral vein. In the current analysis, we assessed the eligibility and success rate of this IOA approach in a cohort of patients with TCVO requiring a tunneled dialysis catheter.

Long-term outcomes of open and endovascular treatment of recurrent carotid artery stenosis - a 16-year retrospective single centre case series.

The aim of this study is to evaluate perioperative as well as long-term outcomes in patients operated with carotid endarterectomy (CEA) or stenting (CAS) due to symptomatic or asymptomatic high-grade restenosis of the internal carotid artery (ICA). In a retrospective analysis of our electronic database including 2980 patients who underwent carotid endarterectomy or stenting due to a symptomatic or asymptomatic high-grade stenosis of the ICA, between 2000 and 2016, we enrolled 111 patients with recurrent ICA stenosis. An ipsilateral 2nd time restenosis (> 80 % in the asymptomatic and > 50 % in the symptomatic patients according to NASCET criteria) of ICA was detected in 13 patients (12 %); 3 of them were symptomatic.

[Review of the proceedings of the 34th Annual Meeting of the German Society for Vascular Surgery and Vascular Medicine (October 17-20, 2018)].

This article is a review of the proceedings of the 34th Annual Meeting of the German Society for Vascular Surgery and Vascular Medicine held in Bonn, Germany, from October 17 to 20, 2018. The programme of the Meeting contained reports concerning treatment of aortic dissections and aneurysms, lower-limb ischaemia, management of wounds in vascular pathology, infection in vascular surgery, carotid artery diseases, venous system pathology, vascular biology, as well as vascular access in patients on programmed haemodialysis.

[30th Annual Meeting of the European Society for Vascular Surgery (Copenhagen, Denmark, september 28-30, 2016)].

The article is a brief review of the proceedings of the 30th Annual Meeting of the European Society for Vascular Surgeons, held on September 28-30, 2016 in Copenhagen, Denmark. The papers presented reported the results of managing patients with pathology of carotid arteries, aortic aneurysms, pathology of peripheral arteries, also discussing current achievements and prospects of methods of treatment of arterial and venous diseases.

Cell coupling mediated by connexin 26 selectively contributes to reduced adhesivity and increased migration.

Gap junction proteins (connexins) have crucial effects on cell motility in many systems, from migration of neural crest cells to promotion of metastatic invasiveness. Here, we show that expression of Cx26 (also known as GJB2) in HeLa cells specifically enhances cell motility in scrape wounding and sparse culture models. This effect is dependent on gap junction channels and is isotype specific [Cx26 enhances motility, whereas Cx43 (also known as GJA1) does not and Cx32 (also known as GJB1) has an intermediate effect].

[Late conversions following endoprosthetic repair of abdominal aortic aneurysms].

Presented herein is a review of the literature concerning late open conversions after endoprosthetic repair of abdominal aortic aneurysms, followed by analyzing the data on frequency and terms of performing late conversions, indications, options of surgical technique, lethality, and remote results.

Stroke/Death Rates Following Carotid Artery Stenting and Carotid Endarterectomy in Contemporary Administrative Dataset Registries: A Systematic Review.

Background: Randomised trials have reported higher stroke/death rates after carotid artery stenting (CAS) versus carotid endarterectomy (CEA). Despite this, the 2011 American Heart Association (AHA) guidelines expanded CAS indications, partly because of the Carotid Revascularization Endarterectomy versus Stenting Trial, but also because of improving outcomes in industry sponsored CAS Registries. The aim of this systematic review was: (i) to compare stroke/death rates after CAS/CEA in contemporary dataset registries, (ii) to examine whether published stroke/death rates after CAS fall within AHA thresholds, and, (iii) to see if there had been a decline (over time) in procedural risk after CAS/CEA.

[Review of the proceedings of the congress "Controversies and updates in vascular surgery" (Paris, France, January 22-24, 2015)].

The article is a brief review of the papers presented at the Congress "Controversies and Updates in Vascular Surgery - CACVS) held in Paris (France) on January 22-24, 2015. An emphasis is placed upon the problems of open and endovascular interventions for aortic aneurysms, lower-limb ischaemia, infection in vascular surgery, pathology of the venous system, choosing an approach for endovascular operations and a vascular access for haemodialysis.

[Review of materials on vascular surgery presented at the Congress of the International Society of Surgery (Helsinki, Finland, August 25-29, 2013)].

The article contains a brief review of the materials concerning vascular surgery presented at the Congress of the International Society of Surgery held on August 25-29, 2013 in Helsinki (Finland), showing the outcomes of open and endovascular operations performed in patients presenting with abdominal aortic aneurysms, lower-limb critical ischaemia, obtained in various clinics. This is followed by determining the prospects of further increasing efficiency of surgical methods of treatment of vascular diseases.

Intercellular redistribution of cAMP underlies selective suppression of cancer cell growth by connexin26.

Connexins (Cx), which constitute gap junction intercellular channels in vertebrates, have been shown to suppress transformed cell growth and tumorigenesis, but the mechanism(s) still remain largely speculative. Here, we define the molecular basis by which Cx26, but less frequently Cx43 or Cx32, selectively confer growth suppression on cancer cells. Functional intercellular coupling is shown to be required, producing partial blocks of the cell cycle due to prolonged activation of several mitogenic kinases.

[The efficacy of arterio-venous fistulas in the treatment diffuse arterial diseases].

The experience of treatment of 32 patients with diffuse peripheral arterial diseases was analyzed. All patients underwent the by-pass surgery with the formation of unloading arterio-venous fistulas. Indications to the formation of A-V fistula was the high peripheral resistance of the vascular wall.

[Substantiation of surgical decision making in congenital lesions involving the inguinal major vessels n injection drug abusers].

The article is dedicated to surgical policy pursued in lesions involving femoral major vessels in the inguinal region, having developed due to long-term abuse of injection narcotic drugs. Analysed herein are the outcomes of surgical management of thirty-one patients presenting with a pulsating haematoma and inguinal pseudoaneurysms of post-injection aetiology. According to the authors' opinion, choosing the appropriate scope of the would-be operation is too complicated largely due to peculiarities of the pyo-necrotic process in this zone.