[Long-term follow-up study of post-COVID-19 patients].

Aim: To evaluate dynamic changes in the lungs, hemostasis system, immune system in different terms after coronavirus pneumonia.

Materials And Methods: Ventilation-perfusion single-photon emission computed tomography/computed tomography (CT), functional methods of lung investigation, evaluation of hemostasis system, immune status and specific humoral immune response were performed and evaluated in different terms after coronavirus pneumonia. A total of 71 patients were examined according to this protocol.

[Chronic obstructive pulmonary disease and cardiovascular comorbidity].

In recent years, a greater understanding of the heterogeneity and complexity of chronic obstructive pulmonary disease (COPD) has come from the point of view of an integrated clinical assessment of severity, pathophysiology, and the relationship with other pathologies. A typical COPD patient suffers on average 4 or more concomitant diseases and every day about a third of patients take from 5 to 10 different drugs. The mechanisms of the interaction of COPD and cardiovascular disease (CVD) include the effects of systemic inflammation, hyperinflation (hyperinflation) of the lungs and bronchial obstruction.

[Cardiorespiratory system in adult patients with mucoviscidosis].

Aim: To study cardiorespiratory system in adult patients with mucoviscedosis.

Material And Methods: External respiration function, echocardiographic and dopplercardiographic evidence were analysed for 22 patients with mucoviscedosis.

Results: 66.

Lungs exposed to nuclear catastrophe: one-year therapeutic programme in Chernobyl liquidators group.

The high prevalence of chronic respiratory problems in cleaning technicians (so-called "liquidators") of the destroyed reactor at Chernobyl and prolonged persistence of inhaled radioactive particles in their lungs suggested a substantial link between radioactive exposure and the diseases observed. Taking into account the importance of the problem, we started this study with the aim of establishing an effective and useful therapeutic program and assessing its efficacy during a one-year period of treatment. Chernobyl liquidators (n = 20) were screened by clinical history, physical examination, lung function test, chest radiograph, electrocardiogram, complete blood cell counts, serum chemistry, immunological blood tests, and complete BAL fluid investigation.

[Respiratory and hemodynamic disorders in the participants in the cleanup of the aftermath of the accident at the Chernobyl Atomic Electric Power Station].

After examination of cardiorespiratory function in 10 males exposed to Chernobyl accident unfavorable factors at the age of 31-45 years suffering from chronic obstructive bronchitis (7 cases) and mixed bronchial asthma (3 cases) it was established that the patients had ventilation disorders of mixed genesis (moderate obstructive and respiratory affections), frequently occurring decreased specific diffusion (DLCO/Va) in normal total diffusion capacity of the lungs, inefficient gas exchange, midly declined left ventricular pump capacity and contractility. In the above patients a relationship was found between parameters of central hemodynamics assessed at echo-CG and severity of ventilation impairment and respiratory insufficiency.

[Current approaches to the early diagnosis of primary subacute infectious endocarditis].

A study of 22 patients with a diagnosis of primary infectious endocarditis based on clinical, laboratory and instrumental (electro-, phono- and echocardiography) investigation showed the fever syndrome and rigors to be the main clinical manifestations of the disease. Echocardiography can contribute to its early diagnosis, while increased erythrocyte sedimentation rate remains the most valuable diagnostic test.

[Dilatation (congestive) cardiomyopathy: clinical aspects, diagnosis and treatment].

Clinical and electrocardiographic manifestations of congestive cardiomyopathy are considered on the basis of observations of 25 patients with this pathology of the myocardium. No clinico-electrocardiographic signs specific for this disease were found. Most characteristic were cardiomegaly, congestive cardiac failure and various disturbances of rhythm and conductivity.