Publications by authors named "Kalliopi Tsapa"
Crit Rev Oncol Hematol
December 2024
Article Synopsis
- Many clinical trials for multiple myeloma focus on surrogate endpoints rather than patient-important outcomes, which are crucial for assessing treatment efficacy.
- A systematic review of 624 randomized controlled trials found that the most common primary outcomes were disease response, progression-free survival (PFS), and overall survival (OS), with OS being emphasized relatively less.
- The study also revealed that trials funded by the pharmaceutical industry were significantly more likely to prioritize PFS, raising concerns about potential biases in reporting outcomes.
