SENSORY RATINGS AND SENSITIVITY TO PERCEPTUAL VARIABLES: NOVEL APPROACH TO EVALUATING SEMANTIC MEMORY IN MILD COGNITIVE IMPAIRMENT.

The lexical-semantic impairments at different levels of semantic processing are often observed in Mild cognitive impairment (MCI). To better understand the nature of the lexical-semantic impairment in MCI, this study included two experiments: a sensory rating task and a lexical decision task. Twenty individuals diagnosed with MCI were recruited as well as eighty healthy subjects to serve as a control group.

Eleven-Year Trends in Lipid-Modifying Medicines Utilisation and Expenditure in a Low-Income Country: A Study from the Republic of Srpska, Bosnia and Herzegovina.

Background: In last two decades, there have been substantial changes in the pattern of lipid-modifying medicines utilisation following the new treatment guidelines based on clinical trials. The main purpose of this study was to analyse the overall utilisation and expenditure of lipid-modifying medicines in the Republic of Srpska, Bosnia and Herzegovina during an 11-year follow-up period and to express its share in relation to the total cardiovascular medicines (C group) utilisation.

Methods: In this retrospective, observational study, medicines utilisation data were analysed between 2010 and 2020 period using the ATC/DDD methodology and expressed as the number of DDD/1000 inhabitants/day (DDD/TID).

Trends in Antihypertensive Medicine Utilization in the Republic of Srpska, Bosnia and Herzegovina: An Eleven-Year Follow-Up.

In last 2 decades, there have been substantial changes in the utilization patterns of antihypertensive medicines following new clinical trials and the introduction of new treatment guidelines. The aim of this study was to analyze utilization and prescribing patterns regarding antihypertensive medicines in the Republic of Srpska, Bosnia and Herzegovina during an 11-years follow-up according to national and European treatment guidelines. In this retrospective, observational study, medicine utilization data were analyzed between 2009-2019 period using the ATC/DDD methodology and expressed as the number of DDD/1,000 inhabitants/day (DID/TID).

Moderating effect of ppar-γ on the association of c-reactive protein and ischemic stroke in patients younger than 60.

Aim: The aim of this study was to evaluate the moderating effect of peroxisome proliferator activated receptor-γ (PPAR-γ) gene variants on the association of serum C-reactive protein level (CRP) and ischemic stroke (IS).

Material And Methods: A total of 114 patients with IS and 135 healthy controls were included.

Results: After adjustment for age, sex, total cholesterol, LDL and HDL cholesterol, triglycerides, hypertension, smoking, body mass index and previous therapy with antihypertensive and/or statins, PPAR-γ had statistically significant moderating effect on association of serum CRP level and IS in patients younger than 60.

Platelet serotonin concentration and trait aggression in veterans with post-traumatic stress disorder: a preliminary study.

Animal and human studies suggest that aggressive behavior may be modulated by brain serotonergic system. Serotonergic (5-HT) dysfunction is associated with post-traumatic stress disorder (PTSD), but also with increased aggression and impulsivity, hallmarks of PTSD. The aim of the study was to investigate the association of platelet 5-HT concentration and various types of aggression and impulsivity in veterans with PTSD.

A non-invasive hidden-goal test for spatial orientation deficit detection in subjects with suspected mild cognitive impairment.

Background: There is a need for highly sensitive and specific tests and biomarkers that would allow preclinical diagnosis of mild cognitive impairment (MCI) and Alzheimer's disease (AD), which would also enable timely intervention.

New Method: We have developed a new system (ALZENTIA) to help detect early MCI, mainly caused by AD. The system is based on a hidden-goal task (HGT) in which the human subject has to find a target that is not visible; as such, the navigation is based on a previously memorized target position, in relation to the starting position (egocentric variant) and/or other navigational landmarks (allocentric variant of the task).

Oxidative status and the severity of clinical symptoms in patients with post-traumatic stress disorder.

Background: The aim of this study was to measure the parameters of oxidative stress in the blood of patients with post-traumatic stress disorder.

Methods: The study included 80 male war veterans who participated actively in the Homeland war in Croatia. Volunteers were divided into two groups: 50 veterans diagnosed with post-traumatic stress disorder and 30 without diagnosis.

Eicosapentaenoic acid in serum lipids could be inversely correlated with severity of clinical symptomatology in Croatian war veterans with posttraumatic stress disorder.

Aim: To explore the association between plasma fatty acids composition and the severity of clinical symptoms in Croatian war veterans with posttraumatic stress disorder (PTSD).

Methods: This cross-sectional study included 62 men diagnosed with PTSD caused by combat activities during the War in Croatia 1991-1995. Clinician-Administered PTSD Scale (CAPS), Hamilton Anxiety Rating Scale (HAM-A), and Hamilton Depression Rating Scale (HAM-D-17) were used.

A validation study of appropriate phonological verbal fluency stimulus letters for use with croatian speaking individuals.

The aim of this study is to determine the word frequency for all thirty letters of the Croatian alphabet and to collect normative data for the letter fluency task in Croatian speakers. Ninety two healthy participants were given each of the Croatian letters, and asked to generate as many words as possible in 60 seconds for each letter Results suggested that participants generated most frequently words starting with the letters as follows: "K", "P", "S" and "M".

Art therapy may be benefitial for reducing stress--related behaviours in people with dementia--case report.

Communication with person with dementia (PWD) is becoming worse and worse during the course of illness, and at the end may be totally lost. Non-pharmacological interventions may be beneficial in increasing the behavioural disturbances which appears frequently during the progression of dementia, and combination of non-pharmacological techniques and drugs is usually more efficacy than psychopharmacs alone. Mr.

[Endopleural hypertension and mediastinal hemorrhage].

The authors describe injured guy with thorax compression, with difficult bones injury, lungs rupture, major air-way, and blood vessel. The authors try to explain how could injured live more than 20-min with such injuries that make one impossible to live.