Publications by authors named "Kalhan T"

Article Synopsis
  • The study investigates how plasma metabolites are linked to the progression of chronic kidney disease in individuals with type 2 diabetes, focusing on kidney function decline measured by eGFR slope.
  • Researchers analyzed data from over 5,000 people, identifying specific elevated levels of lipids and amino acids that influence kidney function, both positively and negatively.
  • The findings suggest that metabolite abnormalities, particularly related to fatty acids, may indicate issues with fat breakdown and are connected to the risk of worsening kidney health in diabetic patients.
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Aim: This study investigated the association between the triglyceride-glucose (TyG) index, a surrogate marker of insulin resistance, and moderate/severe periodontitis and the role of blood pressure as a mediator in this association. A second aim was to assess the role of cardiometabolic conditions such as obesity, hypertension, and dyslipidemia as potential effect modifiers.

Methods: Data from 5733 US adults aged 30-64 years and with complete periodontal examination were analyzed (NHANES 2011-2014).

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Despite development of new technologies for caries control, tooth decay in primary teeth remains a major global health problem. Caries risk assessment (CRA) models for toddlers and preschoolers are rare. Among them, almost all models use dental factors (e.

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Objectives: Numerous caries risk assessment tools have been proposed in the literature, with few validated in preschool children especially those receiving oral rehabilitation under general anaesthesia (GA). Past caries experience, the best predictor thus far, may not be a reliable indicator after effective clinical intervention. Hence, this longitudinal study was aimed to explore the potential role of plaque pH in predicting future caries incidence after GA among preschool children.

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Objectives: Oral rehabilitation under general anaesthesia (GA), commonly employed to treat high caries-risk children, has been associated with high economic and individual/family burden, besides high post-GA caries recurrence rates. As there is no caries prediction model available for paediatric GA patients, this study was performed to build caries risk assessment/prediction models using pre-GA data and to explore mid-term prognostic factors for early identification of high-risk children prone to caries relapse post-GA oral rehabilitation.

Methods: Ninety-two children were identified and recruited with parental consent before oral rehabilitation under GA.

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BackgroundProlonged storage of transfused red blood cells (RBCs) is associated with hemolysis in healthy adults and inflammation in animal models. We aimed to determine whether storage duration affects markers of hemolysis (e.g.

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