Publications by authors named "Kalfon A"

Objectives: To define the clinical and laboratory characteristics and natural history of Leydig cell tumours in order to define a general management plan.

Material And Methods: The files of 10 patients operated for Leydig cell testicular tumour between 1982 and 1996 were studied retrospectively.

Results: In nine out of ten cases, the presenting complaint was gynaecomastia, erectile dysfunction or infertility.

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Hyperprolactinemia is the cause of erectile dysfunction in less than 1% of cases. From 1989 to 1996, 13 patients consulted for erectile disorders associated with hyperprolactinemia. The mean age was 47.

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Rectal prolapse is a rare disorder, which usually affects patients suffering from genital prolapse (rectal prolapse is associated with genital prolapse in 50% of cases). On the basis of a study of the literature and with regard to one case history, the authors set out to explore the simplest and most effective way of treating these two disorders simultaneously. The treatment remains surgical and should combine treatment of the genital prolapse by vaginal route with treatment of the rectal prolapse by means of the Delorme operation.

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Asporogenous mutants from Bacillus sphaericus strains 2297 and 1593-4, blocked at different stages of the sporulation process, were isolated. Two mutants (2297 Aspo30A and 2297 Aspo34) which were blocked early in sporulation did not possess any crystalline inclusions and were poorly toxic to Culex pipiens mosquito larvae. Other mutants (2297 Aspo115, 2297 Aspo24 and 1593-4 Aspo12) which were blocked at later stages synthesized crystal-like inclusions next to the forespores, and were highly toxic to mosquito larvae.

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Sporulation of Bacillus sphaericus strain 2297 in a synchronous liquid culture was studied by electron microscopy. The t0 of sporulation occurred 7 h after the beginning of the lag phase. Crystal-like inclusions first appeared at t2 and reached their final size between t5 and t6.

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