Publications by authors named "Kalenia Marquez"
A unified framework of cell population dynamics and mechanical stimulus using a discrete approach in bone remodelling.
Comput Methods Biomech Biomed Engin
March 2023
Article Synopsis
- Multiphysics models are essential for understanding the relationship between mechanical stimuli and cell population dynamics in bone remodeling, but existing models often lack a discrete approach that is easy to implement.
- * This article combines the Komarova cell population model with the Nackenhorst mechanical stimulus model in a 2D setup, enabling analysis of how mechanical loading affects bone density, including the impact of various regulators.
- * The methodology utilizes finite element analysis in ABAQUS to simulate bone remodeling dynamics, successfully modeling conditions like osteoporosis, demonstrating the effectiveness of the discrete modeling approach.