Genetic effects of 1,2-dibromo-3-chloropropane (DBCP) in Drosophila.

Induction of sex-linked recessive lethal mutations, heritable translocations and genetic crossing-over were studied in Drosophila melanogaster males treated as adults and as embryos with different concentrations of gaseous DBCP. Adults exposed to 30 ppm/hr of the compound did not produce a significant number of sex-linked recessive lethal mutations in treated spermatozoa, spermatids, or spermatocytes. However, at an exposure of 17.

Sensitivity of Drosophila melanogaster to Low concentration of gaseous mutagens: III. Dose-rate effects.

Sex-linked recessive lethal mutations were induced in D melanogaster males by chronic as well as acute treatments of gaseous 1,2-dibromoethane ranging from 2.3 to 31 ppm.hr.

Relative effectiveness of neutrons and X-rays in induction of crossing over in Drosophila males.

Relative biological effectiveness of neutrons vs. X-rays in inducing crossing-over in males of D. melanogaster was investigated using 812 and 834 rad of neutrons and the same dose of X-rays.

Genetic effects of strong magnetic fields in Drosophila melanogaster: II. lack of interaction between homogeneous fields and fission neutron-plus-gamma radiation.

Interaction between mutagenic effects of strong homogeneous magnetic fields and fission neutron-plus-gamma radiation was investigated, using the sex-linked, recessive, lethal test in Drosophila melanogaster. Drosophila males were exposed chronically, for seven days, to a 37,000-G homogeneous magnetic field and/or 3 doses of neutron-plus gamma radiation. Mutations in spermatozoa, spermatids, and spermatocytes were scored.

Sensitivity of Drosophila melanogaster to low concentrations of gaseous mutagens. II. Chronic exposures.

Sex-linked recessive lethal mutations were induced in Drosophila melanogaster males by gaseous 1,2-dibromoethane at concentrations ranging from 0.2 to 2 parts per million. Significant numbers of mutations could be induced at all these concentrations.

Genetic effects of strong magnetic fields in Drosophila melanogaster: I. Homogeneous fields ranging from 13,000 to 37,000 Gauss.

Drosophila melanogaster males were exposed to homogeneous magnetic fields of intensities of 13,000 to 37,000 Gauss as eggs, larvae, pupae and as adults. Sex linked recessive lethals were scored in chromosomes exposed as spermatozoa, spermatids and as spermatocytes. There was no indication of enhanced mutation induction by the magnetic fields.

Sensitivity of Drosophila melanogaster to low concentrations of the gaseous 1, 2-dibromoethane: I. acute exposures.

Drosophila melanogaster males were exposed to gaseous 1, 2-dibromoethane at concentrations lower than those used in aerosol treatments of suspected mutagens by other investigators. Premeiotic stages appear to be more sensitive than postmeiotic stages to gaseous mutagens. At an exposure of 125 ppm .