Publications by authors named "Kalcioglu T"
Article Synopsis
- Developmental anomalies in the cochlea are found in about 25% of individuals with congenital deafness, often with unidentified genetic causes.
- Researchers used exome sequencing and CRISPR/Cas9 technology to create patient-specific stem cell lines to study the effects of genetic variants related to hearing loss.
- When differentiating these stem cells into inner ear organoids, the study revealed significant developmental issues in the gene-edited lines, demonstrating the potential of organoids to validate the effects of genetic variants linked to cochlear malformations.
Unlabelled: Background/aim: To determine the efficacy of lycopene, which is considered an antioxidant agent, in decreasing the cochlear damage induced by cisplatin.
Materials And Methods: A total of 38 rats were randomized into 4 groups: control, cisplatin, cisplatin + lycopene, and lycopene-treated groups. In all groups, the distortion-product otoacoustic emission measurements were performed on days 0, 1, 2, and 5.
Introduction: Pharyngocutaneous fistula is one of the most common nonfatal laryngectomy complications (7.6% to 65% of all total patients). Preoperative radiotherapy, advanced tumor stage, poor preoperative medical status, and concomitant pharyngectomy are usually accepted causative factors in fistula formation.
View Article and Find Full Text PDFEffects of smoking and tobacco on nasal carriage and colonisation rates of Staphylococcus aureus were investigated on 368 healthy males aged between 30 and 40 years old. The study group comprised 100 non-smokers (control group), 91 smokers, and 177 cigarette factory workers (42 smokers, 135 non-smokers). Quantitative cultures were done from the nasal swabs of all participants.
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