The immediate effect of a single whole-body vibration session on balance, skin sensation, and pain in patients with type 2 diabetic neuropathy.

Purpose: Patients with diabetic neuropathy usually suffer from impaired balance, pain, and decreased sole-foot sensation. The present research was designed to appraise the relic of whole-body vibration (WBV) on balance, pain, and sole-foot sensation in diabetic neuropathy patients.

Methods: Present study was a single-blind randomized controlled clinical trial.

Teaching self-efficacy and its effects on quality of bedside teaching: Findings from a multi-center survey.

Introduction: Evidence suggests that the performance of medical students is affected by the quality of teaching of clinical teachers, and the higher teachers' teaching quality leads to better students' clinical performance. Hence, the present research aimed to investigate the association between teaching self-efficacy and quality of bedside teaching among medical teachers.

Methods: This is a cross-sectional study.

Effect of upper extremity constraints on functional and dynamic postural control in children with hemiplegic cerebral palsy.

Purpose: To compare the effects of upper extremity constraints on functional and dynamic postural control in children with hemiplegic cerebral palsy.

Materials And Methods: Twelve children with hemiplegic cerebral palsy and 12 typically developing children ages 5 to 12 years (GMFCS I-II) were evaluated with the Timed Up and Go (TUG) and Biodex Balance System during three upper extremity (UE) conditions: 1) Free UEs (no constraints), 2) Simple UE constraint (unaffected/dominant UE constrained with a sling), and 3) Difficult UE constraint (Simple constraint plus the other UE holding cup of water).

Results: The UE condition had significant effects on Overall Stability Index (OSI) (F = 24.

Non-contrast Cine Cardiac Magnetic Resonance image radiomics features and machine learning algorithms for myocardial infarction detection.

Objective: Robust differentiation between infarcted and normal tissue is important for clinical diagnosis and precision medicine. The aim of this work is to investigate the radiomic features and to develop a machine learning algorithm for the differentiation of myocardial infarction (MI) and viable tissues/normal cases in the left ventricular myocardium on non-contrast Cine Cardiac Magnetic Resonance (Cine-CMR) images.

Methods: Seventy-two patients (52 with MI and 20 healthy control patients) were enrolled in this study.

Recent advances in the pharmacological management of sepsis-associated acute kidney injury.

Introduction: Acute kidney injury is a common occurrence in patients with sepsis and portends a high mortality as well as increased morbidity with numerous sequelae including the development of chronic kidney disease. Currently, there are no specific therapies that either prevent AKI or hasten its recovery. Thus, clinicians typically rely on management of the underlying infection, optimization of hemodynamic parameters as well as avoidance of nephrotoxins to maximize outcomes.

The treatment dilemma in adult patients with peripheral pulmonary artery stenosis of diverse etiologies.

Background: Peripheral pulmonary artery stenosis (PPAS) is a rare and underdiagnosed phenomenon that is reported infrequently in adult patients. Most patients with PPAS have concomitant congenital heart diseases, a history of palliative surgical therapies during childhood, or syndromic characteristics. Acquired cases are rare, and they are underestimated in adulthood and managed inappropriately.

The relationship between fasting plasma glucose in the first trimester of pregnancy and the incidence of gestational diabetes in Iran.

Aims: This study aimed to investigate the relationship between fasting plasma glucose in the first trimester of pregnancy and the incidence of gestational diabetes.

Methods: This descriptive-analytical study was conducted using the merging data from two prospective cohort studies that were carried out from 2015 to 2018 in Ahvaz, southwest of Iran. Logistic regression and ROC curves were used to evaluate the predictive power of risk factors.

Development of a colorimetric sensor array based on monometallic and bimetallic nanoparticles for discrimination of triazole fungicides.

Due to the widespread use of pesticides and their harmful effects on humans and wildlife, monitoring their residual amounts in crops is critically essential but still challenging regarding the development of high-throughput approaches. Herein, a colorimetric sensor array has been proposed for discrimination and identification of triazole fungicides using monometallic and bimetallic silver and gold nanoparticles. Aggregation-induced behavior of AgNPs, AuNPs, and Au-AgNPs in the presence of four triazole fungicides produced a fingerprint response pattern for each analyte.

Biological Applications of Severely Plastically Deformed Nano-Grained Medical Devices: A Review.

Metallic materials are widely used for fabricating medical implants due to their high specific strength, biocompatibility, good corrosion properties, and fatigue resistance. Recently, titanium (Ti) and its alloys, as well as stainless steel (SS), have attracted attention from researchers because of their biocompatibility properties within the human body; however, improvements in mechanical properties while keeping other beneficial properties unchanged are still required. Severe plastic deformation (SPD) is a unique process for fabricating an ultra-fine-grained (UFG) metal with micrometer- to nanometer-level grain structures.

Electroconductive Nanobiomaterials for Tissue Engineering and Regenerative Medicine.

Regenerative medicine aims to engineer tissue constructs that can recapitulate the functional and structural properties of native organs. Most novel regenerative therapies are based on the recreation of a three-dimensional environment that can provide essential guidance for cell organization, survival, and function, which leads to adequate tissue growth. The primary motivation in the use of conductive nanomaterials in tissue engineering has been to develop biomimetic scaffolds to recapitulate the electrical properties of the natural extracellular matrix, something often overlooked in numerous tissue engineering materials to date.

Enzymatic Synthesis of Ricinoleyl Hydroxamic Acid Based on Commercial Castor Oil, Cytotoxicity Properties and Application as a New Anticancer Agent.

Background: New anticancer agents that rely on natural/healthy, not synthetic/toxic, components are very much needed.

Methods: Ricinoleyl hydroxamic acid (RHA) was synthesized from castor oil and hydroxylamine using Lipozyme TL IM as a catalyst. To optimize the conversion, the effects of the following parameters were investigated: type of organic solvent, period of reaction, amount of enzyme, the molar ratio of reactants and temperature.

Green Synthesis of Zeolite/FeO Nanocomposites: Toxicity & Cell Proliferation Assays and Application as a Smart Iron Nanofertilizer.

Purpose: The aim of this study was to prepare zeolite/iron (III) oxide nanocomposites (zeolite/FeO-NCs) as a smart fertilizer to improve crop yield and soil productivity.

Methods: Zeolite/FeO-NCs were successfully produced by loading of FeO-NPs onto the zeolite surface using a quick green precipitation method. The production of zeolite/FeO nanocomposites was performed under a mild condition using environmentally friendly raw materials as a new green chemistry method.

Wound dressings functionalized with silver nanoparticles: promises and pitfalls.

Infections are the main reason why most people die from burns and diabetic wounds. The clinical challenge for treating wound infections through traditional antibiotics has been growing steadily and has now reached a critical status requiring a paradigm shift for improved chronic wound care. The US Centers for Disease Control have predicted more deaths from antimicrobial-resistant bacteria than from all types of cancers combined by 2050.

Autoclave-assisted synthesis of AgNPs in extract and assessment of their cytotoxicity, antibacterial and antioxidant activities.

In this study, the authors synthesised silver nanoparticles (AgNPs) using autoclave as a simple, unique and eco-friendly approach. The effect of extract was evaluated as a reducing and stabiliser agent. According to transmission electron microscopy results, the AgNPs were in the spherical shape with a particle size of ∼17 nm.

A review of small molecules and drug delivery applications using gold and iron nanoparticles.

Conventional cancer treatment techniques show several limitations including low or no specificity and consequently a low efficacy in discriminating between cancer cells and healthy cells. Recent nanotechnology developments have introduced smart and novel therapeutic nanomaterials that take advantage of various targeting approaches. The use of nanotechnology in medicine and, more specifically, drug delivery is set to spread even more rapidly than it has over the past two decades.

Electromyographic activity of the hip and knee muscles during functional tasks in males with and without patellofemoral pain.

Background: Patellofemoral pain (PFP) is a common overuse injury in physically active individuals. It is characterized by anterior knee, retropatellar, or prepatellar pain associated with activities that increase patellofemoral joint stress such as squatting, stair ascending and descending, running, jumping, prolonged sitting, and kneeling. The etiology of PFP is believed to be multifactorial.

Biomedical applications of chitosan electrospun nanofibers as a green polymer - Review.

This review outlines new developments in the biomedical applications of environmentally friendly ('green') chitosan and chitosan-blend electrospun nanofibers. In recent years, research in functionalized nanofibers has contributed to the development of new drug delivery systems and improved scaffolds for regenerative medicine, which is currently one of the most rapidly growing fields in all of the life sciences. Chitosan is a biopolymer with non-toxic, antibacterial, biodegradable and biocompatible properties.