[Preparation and clinical trial of new dried balanced food products "Unipit" for total restorative nutrition].

Designs of 2 types of dried balanced food mixtures ("Unipit-1" and "Unipit-2") intended for complete recovery nutrition of patients with retained and disordered digestive function have been validated. The chemical composition of these products has been presented. The results of clinical trials have proved the high therapeutic effectiveness of "Unipit-1" and "Unipit-2" in rehabilitation of neurosurgical patients.

[An experimental study of the biological value of milk proteins with differing ratios of casein and blood proteins].

To improve amino acid composition and to rise the sum of sulfur-containing amino acids, 5 samples of milk protein with varying ratios of casein and serum proteins (24:76; 45:55; 61:39; 73:27; 94:6) were prepared with the use of the membrane technology under conditions of experimental production. Biological experiments conducted with the use of "growth" and "balance" methods have shown a rise of biological value with the increasing of serum protein share reaching its maximum value at a ratio of 61:39. Further elevation of the serum protein share (73:27; 94:6) led to a decrease of biological value.

[Prospects of using new low-calorie products based on a soybean protein isolate in the prevention and treatment of metabolic diseases].

In an experiment on 14 clinically healthy volunteers (12 women and 2 men) a study was made of the tolerance, assimilation and metabolic effectiveness of high-protein low-calorie food products in dietetic correction of excessive body mass. It has been noted that using soybean protein isolate as a component of low-calorie food is promising.

[Comparative biological value of the proteins comprising the products for the tube and regular feeding of patients with mandibular fractures].

A comparative clinical evaluation was made of the biological effectiveness of protein components in the composition of three types of diet for patients with fractures of the mandible who had received "Ensure" (USA), a product for complete tube feeding; an experimental sample developed at the Institute of Nutrition, Academy of Medical Sciences of the USSR; and a routine clinical diet. The biological effectiveness of the proteins was estimated by some anthropometric and biochemical parameters as well as on the basis of nitrogenous metabolism in the patients. It has been established that the protein content in the routine clinical diets does not meet the high requirements in amino acids of patients with fracture of the mandible.

[Clinical study of the assimilation, tolerance and metabolic effectiveness of protein products combined with a soybean isolate].

Combined product containing soybean isolate 500E (produced by "Ralston Purine Company", USA) were clinically used in 16 patients with hyperlipidemia, type II. The results obtained evidenced a high assimilability (95.5-95.

[Clinico-experimental approaches to studying the hypocholesteremic action of soy proteins].

The effect of diets containing soybean proteins substituting a significant portion of meat proteins was studied in patients with hyperlipidemia, type IIa, and in experiments on rats. It was found that soybean proteins included into the diet induced blood plasma amino acid imbalance, changed the excretion of some amino acids with urine, and significantly diminished the blood plasma cholesterol level. In the experiments on rats a reduced rate was noted in the low-density lipoprotein apoprotein formation and high-density lipoprotein apoprotein regeneration in the blood plasma.

[Effectiveness of tube feeding in neurosurgical patients].

The results of the early use of gastrogavage in 24 neuroresuscitation patients are analysed. The dosage of the feeding and control over its efficacy was exercised by means of appraising energy expenditures and their structure with the use of indirect calorimetry as well as according to the nitrous balance data, biochemical criteria of the alimentary status, and the total lymphocyte count. It is shown that neuroresuscitation patients manifested appreciable changes in energy expenditures and their structure as well.