Fluorescence Entrenched Probe for Onsite Detection of Amoxicillin Residue in Bovine Milk.

A novel fluorescent probe (E)-3-(4-hydroxyphenyl)-2-((pyrene-1-ylmethylene) amino)propanoic acid (PyT) was developed for the 'turn-on' detection of amoxicillin(AM), residues. The PyT molecule was developed by a simple condensation reaction between a biologically important tyrosine amino acid and pyrene carboxaldehyde. The small fluorophore molecule has spectacular photoluminescence properties such as large stock shift, high photostability, selectivity and sensitivity toward the analytes.

AIE paper shred for the detection of evolved amine vapor from putrefaction processes of fish.

Seafood plays a major role in the human diet. During transportation, without proper storage and supply chain, its quality deteriorates easily. The post-harvesting processes such as the storage of food play a crucial role in human health.

Conductivity-Based Gas Sensors Using Polysaccharide-Capped Gold Nanoparticles for the Detection of Volatile Gases.

Gold nanoparticles (Au) were synthesized by a sustainable approach utilizing tamarind seed polysaccharide (TSP). Polysaccharides are naturally occurring polymers derived from tamarind seeds, which function both as capping and reducing agents. Polyaniline (PANI) was subsequently capped over the as-prepared gold nanoparticles in order to facilitate the sensor property.

Pyridine Derivatives as Potential Inhibitors for Coronavirus SARS-CoV-2: A Molecular Docking Study.

Coronavirus SARS-CoV-2, a causative agent for the global epidemic disease COVID-19, which has a highest modality rate. Several initiatives have been undertaken to repurpose current antiviral medications and tested the classic pyridine derivatives (PyDev), which have showed substantial therapeutic potential against a variety of illnesses and also have several biological functions such as, antibacterial, antiviral, and anti-inflammatory. However, limited reports are available for the treatment of Coronavirus SARS-CoV-2 using PyDev.

In Vitro and In Silico Screening of Benzimidazole-Based Ruthenium(II) Complexes as Potent ALK Inhibitor for Cancer Prevention.

Two new heteroleptic Ru(II) polypyridyl complexes, [Ru(bpy)(B)]Cl (RBB) (bpy = 2,2'-bipyridine and B = 4,4'-bis(benzimidazolyl)-2,2'-bipyridine) and [Ru(phen)(B)]Cl (RPB), were synthesized, and the structural features were confirmed by the analytical and spectral tools such as FT-IR, H-NMR, and UV-Visible spectroscopy. We have explored the possibility of improving the selectivity of cytotoxic Ru(II) complex and their preliminary biological evaluation against MCF-7 and MG-63 cell lines and clinical pathogens. The results of the antimicrobial screening show that the ligand and complexes have a range of abilities against the species of bacteria and fungi that were tested.

Exploring the structural interaction of BSA with amine functionalized ruthenium(II) metal complex.

Communicated by Ramaswamy H. Sarma.