Analyzing the Bioactivity of a Novel Bone Cement: An In Vitro Study.

Aim: To analyze the effect of bioactive bone cement (BBC) placed in a phosphate buffer saline solution in comparison to mineral trioxide aggregate (MTA).

Methodology: Ten samples each of BBC (group 1) and MTA (group 2) were prepared and stored in a phosphate buffer saline solution. After three days of storage, white precipitates were formed on the surface of the samples.

Transplantation of hippocampal cell lines restore spatial learning in rats with ventral subicular lesions.

We have demonstrated in our previous studies that ventral subicular lesion induces neurodegeneration of the hippocampus and produces cognitive impairment in rats. In the present study, the efficacy of transplanted green fluorescent protein (GFP)-labeled hippocampal cell line (H3-GFP) cells in establishing functional recovery in ventral subicular lesioned rats has been evaluated. The survival of H3-GFP transplants and their ability to express trophic factors in vivo were also investigated.