Background: Mesenchymal stem cells (MSCs) offer clinical promise for use in cell therapy approaches for regenerative medicine. A therapeutic challenge is that MSCs from different tissues are phenotypically and functionally distinct. Therefore, this study aims to molecularly characterize oral-derived MSCs by defining one of the three hallmarks of MSCs, differentiation potential, to discern their true molecular identities.
View Article and Find Full Text PDFThis paper addresses the relationship between information and structure of the genetic code. The code has two puzzling anomalies: First, when viewed as 64 sub-cubes of a [Formula: see text] cube, the codons for serine (S) are not contiguous, and there are amino acid codons with zero redundancy, which goes counter to the objective of error correction. To make sense of this, the paper shows that the genetic code must be viewed not only on stereochemical, co-evolution, and error-correction considerations, but also on two additional factors of significance to natural systems, that of an information-theoretic dimensionality of the code data, and the principle of maximum entropy.
View Article and Find Full Text PDFDespite the global decline, neonatal mortality rates (NMR) remain high in India. Family members are often responsible for the postpartum care of neonates and mothers. Yet, low health literacy and varied beliefs can lead to poor health outcomes.
View Article and Find Full Text PDFDental caries and periodontal disease are very common chronic diseases closely linked to inadequate removal of dental plaque. Powered toothbrushes are viewed as more effective at removing plaque; however, the conflicting evidence and considerable unexplained heterogeneity in their clinical outcomes does not corroborate the relative merits of powered tooth brushing. To explain the heterogeneity of brushing patterns with powered toothbrushes, we conducted a observational study of tooth brushing practices of 12 participants in their naturalistic setting.
View Article and Find Full Text PDFThis paper shows that below a critical value of dimensionality that lies between two and three, the potential between objects begins to fall as the energy levels increase. For dimensionality below two, the potential becomes constant irrespective of separation and the force between them disappears, which represents a new paradigm of asymptotic freedom. Since asymptotic freedom is at the basis of many applications such as those associated with strange metals, unconventional superconductors, and fractional quantum Hall states, the new paradigm can have novel applications.
View Article and Find Full Text PDFWe present an information-theoretic approach to the optimal representation of the intrinsic dimensionality of data and show it is a noninteger. Since optimality is accepted as a physical principle, this provides a theoretical explanation for why noninteger dimensions are useful in many branches of physics, where they have been introduced based on experimental considerations. Noninteger dimensions correlate with lesser density as in the Hausdorff dimension and this can have measurable effects.
View Article and Find Full Text PDFThis article briefly reviews the biofield hypothesis and its scientific literature. Evidence for the existence of the biofield now exists, and current theoretical foundations are now being developed. A review of the biofield and related topics from the perspective of physical science is needed to identify a common body of knowledge and evaluate possible underlying principles of origin of the biofield.
View Article and Find Full Text PDFThe study was undertaken to investigate the mutagenic activity of hydrazine hydrate a structural isomer of the nucleic acid base thymidine in barley. The treatments were administered alone or in the presence of maleic hydrazide and X-rays. Hydrazine was able to produce chlorophyll mutations in the M1-generation itself if applied alone, in a mixture or as a last treatment in a sequence.
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