Evaluation of optic nerve sheath diameter in patients undergoing robotic hysterectomy in steep Trendelenburg position compared to open abdominal hysterectomy in supine position: A randomized controlled trial.

Background And Aims: Raised intracranial pressure (ICP) is believed to be one of the side effects of prolonged Trendelenburg position in robotic gynecologic surgeries. Optic nerve sheath diameter (ONSD) corresponds to a rise in ICP. However, the data from robotic hysterectomy surgeries is limited.

The prevalence of co-administration of clopidogrel and proton pump inhibitors.

Background: Recent studies have suggested that proton pump inhibitors (PPIs) may inhibit the antiplatelet activity of clopidogrel, increasing the risk of major cardiovascular events in patients taking clopidogrel and PPIs together.

Aim: The primary aim of this study was to determine the prevalence of co-prescription of clopidogrel and PPIs amongst residents of aged-care facilities in New South Wales, Australia.

Methods: One-year prescription records of 791 aged-care residents were analysed for prevalence of co-prescribing of clopidogrel and PPIs, and aspirin with clopidogrel and PPIs.