Association of mannose binding lectin with chronic obstructive pulmonary disease susceptibility and its clinical outcomes.

Background: The physiological interactions of MBL suggest its contribution towards the pathogenesis of COPD.

Objective: The present case-control study was undertaken to elucidate the role of MBL with COPD risk and clinical outcomes in north Indian cohort.

Methods: Patients were enrolled as per GOLD criteria.

A prospective study of the clinical profile of hemoptysis and its correlation with radiological and microbiological findings.

Background: The etiological pattern of hemoptysis has evolved, with pulmonary tuberculosis (PTB) becoming less prevalent as a cause. There is a paucity of literature regarding the spectrum of diseases that present as hemoptysis and the data related to detailed clinical profile are lacking. Hence, this study is taken up to determine the clinical profile of hemoptysis and its correlation with radiological and microbiological findings.

Colonic tuberculosis masquerading as crohn's disease.

Intestinal tuberculosis (TB) is a diagnostic challenge and can closely mimic Crohn's disease (CD) and colon cancer. These disease entities very closely resemble each other in symptomatology, imaging, appearance, and pathology. We present a case of colonic TB where the initial diagnostic workup was suggestive of CD.

Metal organic frameworks for electrochemical sensor applications: A review.

Metal-organic frameworks (MOFs) are broadly known as porous coordination polymers, synthesized by metal-based nodes and organic linkers. MOFs are used in various fields like catalysis, energy storage, sensors, drug delivery etc., due to their versatile properties (tailorable pore size, high surface area, and exposed active sites).

Lichen scrofulosorum: An uncommon manifestation of a common disease.

Tuberculid is a cutaneous immunologic reaction to the presence of tuberculosis (TB), which is often occult, elsewhere in the body or their fragments released from a different site of manifest or past tuberculous infection. These eruptive lesions are due to hematogenous dissemination of bacilli in a host with a high degree of immunity against Mycobacterium tuberculosis. Although rare, these specific lesions are important diagnostic markers of TB.

Esophageal tuberculosis: A rare case report.

After a steady decline throughout the 20 century, the incidence of tuberculosis (TB) in industrialized countries has started to rise again. However, in developing countries like India, the menace of TB had never been controlled. Gastrointestinal (GI) TB is rare, and the GI tract is considered only the sixth most frequent site of extrapulmonary TB.

Comparative study of effect of Withania somnifera as an adjuvant to DOTS in patients of newly diagnosed sputum smear positive pulmonary tuberculosis.

Background: Ashwagandha (Withania somnifera Linn.) a rejuvenative herb has long been used as an immunomodulator in Indian subcontinent. As immunity plays an important role in pathogenesis and treatment of tuberculosis (TB), so role of W.

Profile of adverse drug reactions in drug resistant tuberculosis from Punjab.

Objective: The aim of the study was to elucidate the profile of adverse drug reactions (ADRs) associated with second-line anti-tubercular treatment for drug-resistant tuberculosis.

Material And Methods: ADR profile of diagnosed drug-resistant tuberculosis cases on supervised second-line anti-tubercular drug regimen under Programmatic Management of Drug-resistant Tuberculosis under Revised National Tuberculosis Control Programme, were studied over two years' period. Adverse reactions were categorised into mild, moderate and severe types with subsequent systematic data-analysis.

Manifestations of tuberculosis in elderly versus young hospitalised patients in Amritsar, India.

Setting: Published literature on the clinical characteristics of tuberculosis (TB) among elderly patients in India is scarce, as the problem of geriatric TB has not received the attention it deserves.

Objectives: To compare the manifestations of TB among elderly and young patients.

Design: Medical records of elderly and young TB patients were extracted and compared.

Conservative management of post traumatic thoraco diaphragmatico biliary fistula.

We report herein a case of thoraco diaphragmatico biliary fistula in a 24-year-old male who was managed conservatively with antibiotics and tube thoracostomy and had complete radiological clearance.

Association of P2X7 receptor +1513 (A-->C) polymorphism with tuberculosis in a Punjabi population.

Background: Development of tuberculosis (TB) disease is an outcome of complex host-pathogen interactions. The purinergic P2X(7) receptors are adenosine triphosphate gated molecules shown to induce killing of intracellular Mycobacterium tuberculosis, followed by apoptosis of the infected macrophage. A single nucleotide polymorphism in exon 13 of the P2X(7) receptors gene at +1513 position has been shown to abolish the function of this receptor and to be associated with increased susceptibility to TB in some ethnic groups.

A study of changes in the body composition components in the patients with pulmonary tuberculosis.

The present study deals with the analysis of body composition components of 86 randomly selected patients with confirmed pulmonary tuberculosis aged 16- 70 years collected from the District Tuberculosis Centre and Hospital, Amritsar. An adequate number of controls were also taken for comparison. The findings of the present study showed highly significant differences (p < or = 0.

Genetic diversity in clinical Mycobacterium tuberculosis isolates from Punjab.

Setting: Two hospitals, Sri Guru Ram Das Institute of Medical Sciences and Research and the TB and Chest Hospital, Amritsar, Punjab.

Objective: To explore genetic diversity among the clinical Mycobacterium tuberculosis isolates prevalent in Punjab.

Design: Fifty-six random clinical isolates of M.