Publications by authors named "Kajal Gandhi"

Article Synopsis
  • * The text discusses key psychedelic substances (e.g., psilocybin, MDMA, LSD) and their therapeutic potential, mechanisms, and the current regulatory landscape involving their legal status, particularly their classification as Schedule I substances.
  • * Regulatory bodies like the FDA and EMA are monitoring psychedelic development closely, emphasizing the need for careful regulation to ensure safety, efficacy, and the therapeutic benefits of these drugs.
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This large type 1 diabetes cohort study showed that insulin pump utilization has increased over time and that use differs by sex, insurance type, and race/ethnicity. Insulin pump use was associated with more optimal A1C, increased use of continuous glucose monitoring (CGM), and lower rates of diabetic ketoacidosis and severe hypoglycemia. People who used an insulin pump with CGM had lower rates of acute events than their counterparts who used an insulin pump without CGM.

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  • Brainstem injury can develop in up to 2% of children after receiving radiation therapy to the posterior fossa, potentially occurring months or even years post-treatment.
  • Young age (under 5 years) and pre-existing health issues like cerebrovascular disease, diabetes, and hypertension increase the risk of this injury.
  • Radiation necrosis, which can be serious and fatal, has been linked to a specific genetic mutation (RNF213) that is also associated with moyamoya disease, hinting at a genetic predisposition to this complication.
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We identified characteristics associated with continuous glucose monitoring (CGM) use in women of reproductive age with type 1 diabetes (T1D) in the T1D Exchange clinic registry from 2015 to 2018. Among 6643 assessed women, the frequency of CGM increased from 2015 to 2018 (20.6% vs.

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Health care inequities among racial and ethnic groups remain prevalent. For people with type 1 diabetes who require increased medical access and care, disparities are seen in access to care and health outcomes. This article reports on a study by the T1D Exchange Quality Improvement Collaborative evaluating differences in A1C, diabetic ketoacidosis (DKA), severe hypoglycemia, and technology use among racial and ethnic groups.

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  • A study is looking at how wearing ankle weights can help new moms with gestational diabetes lose weight and lower their risk of developing type 2 diabetes in the future.
  • The Moms in Motion study involves 160 women who will either wear ankle weights during daily activities or receive regular care without the weights for 6 months.
  • The researchers will check how effective the ankle weights are by measuring weight loss, changes in body composition, and other health markers before and after the study.
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Introduction: Patient outcomes resulting from optimal type 1 diabetes (T1D) care have historically focused on driving a single metric, hemoglobin A. Our objectives were to design, build, and launch an aggregate clinical indicator that comprehensively reflects patient management status beyond hemoglobin A alone. This project aimed to show proof of principle that an aggregate score comprised of T1D outcome metrics could be built to track quality performance.

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Objectives: The American Diabetes Association (ADA) and the International Society for Pediatric and Adolescent Diabetes (ISPAD) have outlined standards for best practices in providing optimal diabetes care to children with type 1 diabetes (T1D). Our objectives were to design a metric that evaluated delivery of optimal diabetes care and to use this metric to drive improvement within our diabetes program.

Methods: Using published guidelines, we identified 11 elements of optimal diabetes care that should be reliably delivered at our institution as standard-of-care.

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Hypoglycemia is a heterogeneous disorder with many different possible etiologies, including hyperinsulinism, glycogen storage disorders, fatty acid disorders, hormonal deficiencies, and metabolic defects, among others. This condition affects newborns to adolescents, with various approaches to diagnosis and management. This paper will review current literature on the history of hypoglycemia, current discussion on the definition of hypoglycemia, as well as etiologies, diagnosis, and management.

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Latino and Asian-Americans represent the fastest growing immigrant populations in the United States. We aimed to review the current knowledge on the psychosocial factors that influence type 1 diabetes (T1D) care, education, and outcomes in Latino and Asian-American youth immigrants in the United States, as well as culturally sensitive programs to address health disparities. We conducted a narrative, conceptual review of studies on T1D in Latino and Asian-American youth and relevant studies in type 2 diabetes and adults.

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Suboptimal adherence remains a significant concern for adolescents with Type 1 diabetes, the treatment regimen for which is complex and includes numerous behaviors. Accurate assessment of adherence is critical for effective healthcare and to measure trial outcomes. Without a valid biomarker of adherence, assessment strategies must rely on measuring management behaviors.

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