Publications by authors named "Kaiyun Wu"

Core-shell particles have been widely used in improving the toughness of resin, but a convenient and efficient large-scale preparation method for core-shell particles is lacking currently. In this work, an efficient and simple method has been developed to fabricate core-shell particles by combining photopolymerization and phase separation inside the emulsion droplet. In this strategy, two photocurable prepolymers with different hydrophilicity were dissolved in a cosolvent and dispersed in an aqueous solution to form an emulsion.

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Objective: To identify related factors that affect the ovarian reserve after laparoscopic ovarian cystectomy in patients with endometriomas.

Study Design: It was a retrospective cohort study performed in a tertiary-care university hospital. A total of 409 patients with endometriomas underwent laparoscopic ovarian cystectomy between June 2014 and November 2021.

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Maxim is a high-value species of fruit oil with edible, abundant linoleic acid and polyphenols. is described as a dioecious species, and the flowers are male; female and bisexual flowers are produced on separate plants. In order to explore the flower types of , the morphology of its flowers and inflorescence were investigated in this study.

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In this work, a smart self-healing coating with long-term anticorrosion ability was developed based on multiresponsive polyaniline (PANI) porous microspheres. The polyaniline porous microspheres loaded with corrosion inhibitor (benzotriazole, BTA) was prepared by the emulsion template method and photopolymerization. The BTA loaded in the polyaniline microspheres acted as a corrosion inhibitor, while the polyaniline in the shell performed the multiple functions of corrosion inhibition, pH-responsive and photoresponsive release, and photothermal conversion.

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Article Synopsis
  • The study examines how the digestion of soybean protein changes when treated with phytase, an enzyme that reduces phytate levels in the protein.
  • Results showed that phytase treatment improved the solubility of soybean protein and shifted its isoelectric point, which helps the protein dissolve better in acidic conditions.
  • The findings suggest that using phytase leads to a faster digestion rate and less aggregation of the protein, making it potentially more effective for clinical nutrition and specialized medical foods.
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Article Synopsis
  • - Atherosclerosis leads to cardiovascular diseases due to the buildup of oxidized lipoproteins (ox-LDL) in arteries, promoting inflammation and plaque formation.
  • - Hydrogen sulfide (HS) shows promise as an anti-inflammatory agent; it reduces the uptake of ox-LDL by macrophages, while another compound, propargylglycine (PPG), increases this process.
  • - HS down-regulates receptors involved in ox-LDL uptake, specifically CD36 and SR-A, through the NF-κB signaling pathway, suggesting its potential as a therapeutic target in early atherosclerosis development.
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Persimmon fruits are brightly colored and nutritious and are fruits that contain large amounts of sugar, vitamins, mineral elements, and phenolic substances. The aim of this study was to explore the differences in fruit-sugar components of different persimmon germplasms and their relationships with phenotypic and flavor indices through the determination of phenotypes and sugar components and through electronic-tongue indices, which provided the basis and inspiration for the selection of different sugar-accumulating types of persimmon fruits and the selection of high-sugar persimmon varieties. Our results showed that persimmon germplasm fruit-sugar components were dominated by sucrose, glucose and fructose and that the remaining sugar components were more diverse but less distributed among the various germplasm types.

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Cervical cancer is a significant public health concern, particularly in low- and middle-income countries where resources for prevention and treatment are limited. Routine screening, such as the Papanicolaou test (Pap smears) and human papillomavirus (HPV) testing, plays a crucial role in the early detection and prevention of cervical cancer. However, the participation rate in cervical cancer screening programs remains below optimal levels due to various factors.

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In this work, graphene oxide (GO)/polymer hybrid microcapsule-loaded self-healing agents were prepared via the combination of the emulsion template method and photopolymerization technology. The incorporation of GO in the microcapsule shell not only improved the impermeability, mechanical property, and solvent resistance property of the microcapsules significantly but also endowed the microcapsules with photothermal conversion property. By incorporating GO/polymer hybrid microcapsules in water-borne epoxy resin, a novel kind of anticorrosion coating with a double self-healing property was successfully fabricated.

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Plant-based meat analogs have increasingly attracted the attention of the food industry in recent years. However, the digestion behavior of this innovative solid food in human stomach is poorly understood. In this study, plant-based meat analogs with different internal structures were prepared with/without high-moisture extrusion technology and at different temperatures.

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The common belief that heat treatment enhances the gastric digestion of proteins is largely based on findings from animal proteins and may not apply to all proteins, particularly plant proteins. Here, we compared the digestion characteristics of soybean protein isolates (SPI) in an semi-dynamic digestion model and found distinct effects of heat treatment on the digestion properties of plant proteins. The results revealed that heat-treated SPIs formed clots during the early stages of digestion, although the clots gradually became smaller and looser as digestion progressed, the systems remained turbid at the end of gastric digestion, indicating the lag in their emptying.

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With the rising need for accessible cervical cancer screening, self-sampling methods offer a promising alternative to traditional physician-led sampling. This study aims to evaluate the efficacy of the HygeiaTouch Self Sampling Kit for Women in detecting human papillomavirus (HPV) types and predicting cervical lesions. We studied the concordance in identifying high-risk HPV (hrHPV) types between samples collected by physicians and those self-collected by women using a self-sampling kit for validation.

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Steroid cell tumors, not otherwise specified (SCT-NOS), are uncommon ovarian neoplasms accompanied by virilization symptoms due to hyperandrogenism, which are malignant in approximately one-third of the cases. Given the rarity of SCT-NOS, their molecular underpinnings have not yet been studied in depth. In this case series, we performed the first comprehensive analysis of the genetic landscape of this rare ovarian tumor.

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AMPK: AMP-activated protein kinase; CHX: cycloheximide; RAD001: everolimus; HBSS: Hanks' balanced salt solution; LC-MS/MS: liquid chromatography-mass spectrometry/mass spectrometry; MMP14: matrix metallopeptidase 14; MTOR: mechanistic target of rapamycin kinase; MAPK: mitogen-activated protein kinase; RB1CC1/FIP200: RB1 inducible coiled-coil 1; PtdIns3P: phosphatidylinositol-3-phosphate; PX: phox homology; SH3: Src homology 3; SH3PXD2A/TKS5: SH3 and PX domains 2A; SH3PXD2A-[6A]: S112A S142A S146A S147A S175A S348A mutant; ULK1: unc-51 like autophagy activating kinase 1.

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Objective: To evaluate the regression rate of endometrial polyps (EPs) in a cohort of asymmetric women after conservative follow-up.

Materials And Methods: In this retrospective cohort study, a total of 1006 women with asymptomatic EPs were treated with expectant management or hormonal drugs between June 1999 and May 2018. Four hundred forty-eight women (44.

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In this work, a series of polymer microcapsules based on UV-curable prepolymers are prepared by combining an emulsion template and photopolymerization. The modulation of the shell structure is achieved by employing UV-curable prepolymers with different chemical structures (polyurethane acrylates, polyester acrylates, and epoxy acrylates) and functionalities (di-, tetra-, and hex-). The relationships between the shell structure and the microcapsule properties are investigated in detail.

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Objectives: Diospyros oleifera, one of the most economically important Diospyros species, is an ideal model for studying the fruit development of persimmon. While, the lack of whole-transcriptome has hindered the complex transcriptional regulation mechanisms of sugar and tannin during fruit development.

Data Description: We applied Oxford Nanopore Technologies to six developmental stage of fruit from D.

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It is well known that the main forms of innervation are synapses and free nerve endings, while other forms of innervation have not been reported. Here, we explore a new way of innervating lymphoid organs. Male Sprague-Dawley rats were used for studying the innervation of sympathetic nerve fibers in lymph nodes by means of anterograde tracking, immunoelectron microscopy, three-dimension reconstruction analysis, and immunofluorescence labeling.

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In this study, a facile one-pot strategy was developed to prepare porous polymeric microspheres photopolymerization, where organic solvents functioned as porogens. In this strategy, an oil phase containing organic solvents and photopolymerizable materials was stabilized in water to form a stable oil-in-water emulsion. Upon UV irradiation, the photopolymerizable materials (photosensitive monomers/photosensitive prepolymers) underwent polymerization to form microspheres and the subsequent removal of organic solvents left pores in microspheres, leading to the generation of porous polymeric microspheres with high yielding.

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Background: Endometrial hyperplasia (EH), particularly with atypia, is considered an antecedent of endometrial adenocarcinoma. In this study, we aimed to apply massively parallel sequencing of endometrial lavage specimens for the detection of cancer-associated mutations in atypical (AEH) and non-atypical endometrial hyperplasia (NEH). The identified alterations were compared with those detected in tissue samples.

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The pathogenic influences of uterine bacteria on endometrial carcinogenesis remain unclear. The aim of this pilot study was to compare the microbiota composition of endometrial lavage samples obtained from women with either endometrial hyperplasia (EH) or endometrial cancer (EC) those with benign uterine conditions. We hypothesized that specific microbiota signatures would distinguish between the two groups, possibly leading to the identification of bacterial species associated with endometrial tumorigenesis.

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We aimed to detect endometrial cancer (EC)-associated mutations in endometrial lavage specimens collected in an office setting and to compare the detected mutations with those identified in tissue samples. Participants included 16 women attending for an office hysteroscopy because of suspected EC between July 2020 and October 2021. Massively parallel sequencing was conducted using the targeted 72 cancer-associated genes.

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Plant mitochondrial genomes are a valuable source of genetic information for a better understanding of phylogenetic relationships. However, no mitochondrial genome of any species in Ebenaceae has been reported. In this study, we reported the first mitochondrial genome of an Ebenaceae model plant .

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Background: Extracellular and cell-surface molecules remain the most common druggable cancer targets. However, intracellular therapeutic modalities are gaining momentum. The overexpression of stress-induced phosphoprotein 1 (STIP1), an adaptor protein that coordinates the functions of different chaperones in protein folding, has been reported in several solid malignancies.

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cv is a rare germplasm of Linn in the world. In this study, we generated the complete chloroplast (cp) genome of . cv.

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Synopsis of recent research by authors named "Kaiyun Wu"

  • - Kaiyun Wu's recent research spans multiple fields, including plant biology, materials science, and biomedical applications, focusing on topics such as the morphological investigation of flowering plants, the development of advanced self-healing coatings, and the nutritional dynamics of plant proteins.
  • - A key finding includes the discovery of flower types and dynamic mineral changes in a high-value fruit oil species, as well as the creation of smart anticorrosive coatings with enhanced properties through innovative use of multiresponsive materials.
  • - Additionally, research on digestive behaviors of plant proteins and the evaluation of self-sampling methods for cervical cancer screenings highlights Wu's contributions to understanding nutritional value in plant-based foods and improving healthcare accessibility through advanced diagnostic techniques.

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