Association of social support with depression and anxiety among the migrant population of Henan, China: Based on a large cross-sectional study.

Amid China's rapid urbanization, the growing migrant population has increasingly drawn attention due to the rising prevalence of mental health concerns. Based on a large cross-sectional study, we explored the relationship between social factors and depression and anxiety among the migrant population and also quantified the correlations of different dimensions of social support and the varying levels of depression and anxiety. Results showed that the prevalence of depression and anxiety are 47.

Development and validation of a sensitive LC-MS/MS method for the assay of four PARP inhibitors in human plasma and its application in ovarian cancer patients.

PARP inhibitors have demonstrated marked efficacy in ovarian cancer patients with BRCA1/2 loss-of-function mutations. In this study, we established and validated a liquid chromatography-tandem mass spectrometry (LC-MS/MS) based method to simultaneously quantify the four frequently prescripted PARP inhibitors, namely niraparib, olaparib，fluzoparib, and pamiparib, in ovarian cancer. The mobile phase was 50 % methanol with 0.