TiRobot-assisted versus freehand femoral neck system placement in the treatment of femoral neck fractures: a systematic review and meta-analysis.

The purpose of this study is to assess the safety and effectiveness of TiRobot-assisted treatment for femoral neck fractures, in comparison to traditional freehand treatment methods. Throughout the research process, we conducted an extensive literature search across numerous databases, including PubMed, EMBASE, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), CQVIP, and Wanfang. Based on the literature screening criteria, we selected six studies, encompassing 358 cases of femoral neck fracture patients, for this meta-analysis.

Factors, mechanisms and improvement methods of muscle strength loss.

Muscle strength is a crucial aspect of muscle function, essential for maintaining normal physical activity and quality of life. The global aging population coupled with the increasing prevalence of muscle disorders and strength loss, poses a remarkable public health challenge. Understanding the mechanisms behind muscle strength decline is vital for improving public health outcomes.

Multi-Omics Analysis of the Effects of Soil Amendment on Rapeseed ( L.) Photosynthesis under Drip Irrigation with Brackish Water.

Drip irrigation with brackish water increases the risk of soil salinization while alleviating water shortage in arid areas. In order to alleviate soil salinity stress on crops, polymer soil amendments are increasingly used. But the regulation mechanism of a polymer soil amendment composed of polyacrylamide polyvinyl alcohol, and manganese sulfate (PPM) on rapeseed photosynthesis under drip irrigation with different types of brackish water is still unclear.

Protective effects of polymer amendment on specific metabolites in soil and cotton leaves under cadmium contamination.

Polymer materials have great potential for soil heavy metal contamination remediation, but the metabolic mechanism by which polymer amendments regulate the responses of soil-plant systems to cadmium (Cd) stress is still unclear. To clarify the metabolic mechanism by which a self-developed soluble polymer amendment (PA) remediates Cd contamination in cotton fields, the common and differential metabolites in soil and cotton leaves were analyzed during the critical period of cotton growth (flowering and bolling stage) in a field experiment. The results showed that Cd stress increased Cd concentration in the soil-cotton system, and reduced enzyme activity in soil and cotton leaves.

Deficit irrigation combined with nitrogen application in the early growth stage of sugar beet increases the production capacity of canopy and avoids yield loss.

Background: Properly reduced irrigation combined with nitrogen (N) application can be used to improve crop water use efficiency (WUE) in arid regions, but its effect on sugar beet is unknown at present. A two-year field experiment was conducted to evaluate the effects of N application (N0, 0; N1, 150; N2, 225 kg N ha ) on the canopy production capacity (CPC), yield and WUE of sugar beet under normal irrigation (W1, 70% of field capacity (FC)) and deficit irrigation (DI) (W2, 50% FC) in the early growth stage (EGS).

Results: The results showed that the W2 treatment reduced the CPC by reducing gas exchange, leaf area index (LAI) and chlorophyll content (SPAD value) of sugar beet leaves compared to the W1 treatment.

The Influence of Different Modes of Exercise on Healthy and Injured Tendons.

Tendons are essential components of the musculoskeletal system that links the skeletal muscle to the skeleton. This dense connective tissue exhibits great plasticity. Therefore, research on the influence of types of exercise, including acute and long-term training, on the structural and mechanical properties of tendons in athletic and sedentary populations is of critical importance in the design of scientific-based exercise plans and effective tendinopathy treatment.

Incidence risk of peripheral edema in cancer patients treated with PD-1/PD-L1 inhibitors: A PRISMA guideline systematic review and meta-analysis.

Purpose: To elucidate the relationship between peripheral edema and programmed cell death-1/programmed cell death ligand 1 (PD-1/PD-L1) inhibitors, the meta-analysis was performed.

Method: Following the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-analyses, all-grade and grade 3-5 of peripheral edema data extracted from clinical trials were taken into account for the final comprehensive assessments.

Results: Twenty-seven PD-1/PD-L1-related clinical trials with peripheral edema data were collected.

Integrated Transcriptomic and Metabolomic Analysis of the Mechanism of Foliar Application of Hormone-Type Growth Regulator in the Improvement of Grape ( L.) Coloration in Saline-Alkaline Soil.

(1) Background: To solve the problems of incomplete coloration and quality decline caused by unreasonable use of regulators in grapes, this study clarified the differences in the effects of a hormone-type growth regulator (AUT) and two commercial regulators on grape coloration and quality through field experiments. (2) Methods: The color indexes (brightness (L*), red/green color difference (a*), yellow/blue color difference (b*), and color index for red grapes (CIRG)) of grape fruit were measured using a CR-400 handheld color difference meter. The titratable acid content, total phenol content, and total sugar content were measured using anthrone colorimetry, folinol colorimetry, and NaOH titration, respectively, and the chalcone isomerase activity, phenylalanine ammoniase activity, dihydroflavol reductase activity, and anthocyanin content were measured using a UV spectrophotometer.

Risk of Rash in PD-1 or PD-L1-Related Cancer Clinical Trials: A Systematic Review and Meta-Analysis.

Background: Given that immune-related rash was the most frequently reported PD-1 or PD-L1-related skin toxicity, this systematic review and meta-analysis were conducted to elucidate its incidence risk.

Methods: The meta-analysis was carried out according to the PRISMA guidelines. The random effect model was used in the process of all analyses.

Transcriptomic and Metabolomic Analyses Reveal the Differential Regulatory Mechanisms of Compound Material on the Responses of to Saline and Alkaline Stresses.

Oilseed rape not only has the function of improve saline and alkaline soils, but also alleviate the local feed shortage. However, medium- and high-degree soil salinization and alkalinization always inhibit the growth of oilseed rape. Studies have shown that compound material can improve the tolerance to saline and alkaline stress of crops, but the difference in the regulation mechanism of compound material on oilseed rape in saline and alkaline soils is not clear.

Quantifying influences of administrative division adjustment on PM pollution in China's mega-urban agglomerations.

China's mega-urban agglomerations have experienced severe particulate matter pollution that is accompanied by rapid economic growth and extensive administrative division adjustment (ADA). However, the precise roles of ADA on the environmental quality are unknown. Using the geographical detector and evolution tree model, this study quantifies the effects and mechanisms of ADA on the changes in PM concentration in three mega-urban agglomerations: Beijing-Tianjin-Hebei (BTH), Yangtze River Delta (YRD), and Pearl River Delta (PRD) during 2000-2017.

Polymer amendment regulates cadmium migration in cadmium contaminated cotton field: Insights from genetic adaptation and phenotypic plasticity.

Polymer materials have been widely used in the remediation of soil heavy metal contamination for their good performance in the absorption of metal ions. To reveal the effect of polymer amendment (PA) on the remediation of cadmium-contaminated cotton fields, the cadmium (Cd) fractions in soil, Cd concentration in cotton organs, bioconcentration factor (BCF) of Cd, translocation factor (TF) of Cd, and the antioxidant capacity and photosynthesis of functional leaves were evaluated combining with the transcriptomic and metabolomic analyses, in barrel experiments in the field at the flowering and boll-forming stage of cotton. The results showed that, cotton improved the tolerance to Cd through self-regulation in Cd-contaminated soil.

Urban ecological land and natural-anthropogenic environment interactively drive surface urban heat island: An urban agglomeration-level study in China.

The surface urban heat island effect (SUHI) that occurs during rapid urbanization increases the health risks associated with high temperatures. Urban ecological land (UEL) has been shown to play an important role in improving urban heat stress, however, the impact of UEL interactions with the natural-anthropogenic environment on SUHI at the urban agglomeration-scale is less explored. In this study, the Google Earth Engine and GeoDetector were applied to characterize the spatiotemporal patterns of UEL and SUHI in the Guangdong-Hong Kong-Macao Greater Bay Area from 2000 to 2020 by extracting major built-up urban areas and quantifying the impacts of UEL and its interactions with the natural-anthropogenic factors on SUHI.

Metabolic regulation in soil microbial succession and niche differentiation by the polymer amendment under cadmium stress.

Cadmium (Cd) contamination seriously threatens the agricultural production, so exploring the response of soil microenvironment to amendments in Cd-contaminated soils is of importance. In this study, the mechanism of remediation of Cd-contaminated soil using the polymer amendment was studied in cotton flowering stage. The results showed that the concentration of Cd in cotton root and various Cd forms in Cd-contaminated soils were obviously high.

Spatial-temporal patterns and influencing factors of ecological land degradation-restoration in Guangdong-Hong Kong-Macao Greater Bay Area.

Despite the fact that urban agglomerations have undergone extensive ecological land coverage modifications, exploration of the patterns and driving mechanisms associated with ecological land degradation (ELD) and ecological land restoration (ELR) in urban agglomerations is still limited. This study combined remote sensing technology, as well as landscape index and geographical detector to characterize the spatiotemporal patterns of ELD (isolating, adjacent, and enclosing degradation) and ELR (outlying, edge-expansion, and infilling restoration) in the Guangdong-Hong Kong-Macao Greater Bay Area (GBA) from 1990 to 2019. Subsequently, the contributions, interactions, and driver changes were quantified.

Effects of Organic Polymer Compound Material on K and Na Distribution and Physiological Characteristics of Cotton Under Saline and Alkaline Stresses.

Soil salinization and alkalization greatly restrict crop growth and yield. In this study, NaCl (8 g kg) and NaCO (8 g kg) were used to create saline stress and alkaline stress on cotton in pot cultivation in the field, and organic polymer compound material (OPCM) and stem girdling were applied before cotton sowing and at flowering and boll-forming stage, respectively, aiming to determine the effects of OPCM on K and Na absorption and transport and physiological characteristics of cotton leaf and root. The results showed that after applying the OPCM, the Na content in leaf of cotton under saline stress and alkaline stress were decreased by 7.

[How Different Ratios of Straw Incorporation to Nitrogen Fertilization Influence Endogenous and Exogenous Carbon Release from Agricultural Soils].

The adjustment of the C/N ratio by straw combined with fertilizer nitrogen (N) not only affects straw decomposition but also affects soil organic carbon (SOC) decomposition, i.e. the priming effects.

Application of compound material alleviates saline and alkaline stress in cotton leaves through regulation of the transcriptome.

Background: Soil salinization and alkalinization are the main factors that affect the agricultural productivity. Evaluating the persistence of the compound material applied in field soils is an important part of the regulation of the responses of cotton to saline and alkaline stresses.

Result: To determine the molecular effects of compound material on the cotton's responses to saline stress and alkaline stress, cotton was planted in the salinized soil (NaCl 8 g kg) and alkalized soil (NaCO 8 g kg) after application of the compound material, and ion content, physiological characteristics, and transcription of new cotton leaves at flowering and boll-forming stage were analyzed.

Study on the effects of polymer modifiers and phloem girdling on cotton in cadmium-contaminated soil in Xinjiang Province, China.

The effects of two liquid modifiers (polyacrylate compound modifier and organic polymer compound modifier) and phloem girdling (stem girdling and branch girdling) on cadmium (Cd) content, Cd transport, and photosynthetic parameters of cotton (Xinluzao 60) in Cd-contaminated soil (40 mg kg ) were studied through barrel experiment. The results showed that the distribution ratios of Cd in stem, leaves, and bolls, leaf net photosynthetic rate (Pn), leaf stomatal conductance (Gs), leaf transpiration rate (Tr), and chlorophyll content were decreased after girdling; and the application of modifiers reduced the Cd content and the Cd transported to the shoot, while alleviating photosynthetic damage caused by girdling. In general, our results indicated that the inhibition of carbohydrate supply caused by girdling reduced the photosynthetic capacity of cotton, while the applications of the two liquid modifiers decrease the influence to cotton photosynthesis.

Precise large deviations for widely orthant dependent random variables with different distributions.

Let [Formula: see text] be a sequence of random variables with different distributions [Formula: see text]. The partial sums are denoted by [Formula: see text], [Formula: see text]. This paper mainly investigates the precise large deviations of [Formula: see text], for the widely orthant dependent random variables [Formula: see text].

Induction of autophagy by cystatin C: a potential mechanism for prevention of cerebral vasospasm after experimental subarachnoid hemorrhage.

Background: Studies have demonstrated that autophagy pathways are activated in the brain after experimental subarachnoid hemorrhage (SAH) and this may play a protective role in early brain injury. However, the contribution of autophagy in the pathogenesis of cerebral vasospasm (CVS) following SAH, and whether up-regulated autophagy may contribute to aggravate or release CVS, remain unknown. Cystatin C (CysC) is a cysteine protease inhibitor that induces autophagy under conditions of neuronal challenge.

Potential role of CD34 in cerebral vasospasm after experimental subarachnoid hemorrhage in rats.

Inflammatory responses have been implicated in the elaboration of several forms of central nervous system injury, including cerebral vasospasm after subarachnoid hemorrhage (SAH). A critical event participating in such responses is the recruitment of circulating leukocytes into the inflammatory site. CD34 is a key adhesion molecule responsible for recruitment of monocytes/macrophages and the attachment of leukocytes to endothelial cells.