Coculture Strategy for Developing PS23 Fermented Milk with Anti-Colitis Effect.

Few studies have documented the effects of fermented milk on intestinal colitis, which are mediated by regulating various microbial and inflammatory processes. Here, we investigated the effects of fermented milk with PS23 on intestinal epithelial cells in vitro and dextran sulfate sodium (DSS)-induced colitis in vivo. As PS23 grew poorly in milk, a coculture strategy with yogurt culture was provided to produce fermented milk (FM).