Safety Analysis of Adverse Events of Ultrasound Contrast Agent Lumason/SonoVue in 49,100 Patients.

This study assessed the incidence of mild, moderate and severe adverse events (AEs) and examined their association with age, sex, body region examined, time to event and duration of the AE(s) in a large cohort of patients who underwent contrast-enhanced ultrasound (CEUS) with Lumason/SonoVue. In this retrospective observational study, 49,100 patients who underwent CEUS were analyzed. Forty-three (0.

The nickel phosphate rods derived from Ni-MOF with enhanced electrochemical activity for non-enzymatic glucose sensing.

In this work, spherical Ni-based metal-organic frameworks (Ni-MOFs) were used as precursors for preparing nanorod-like nickel phosphate (r-NiPO) with enhanced electro-catalytic properties in detection of glucose. It was found that the addition of nickel ion has a profound effect on construction of nickel phosphate with flower-like, rod-like, and ribbon-like structure in presence of HPO. The r-NiPO consisted of multiple phases of nickel phosphate showed porous, interconnected structure and abundant active Ni(II)/Ni(III) pairs, which was beneficial to facilitate glucose oxidation.