GO-MAE: Self-supervised pre-training via masked autoencoder for OCT image classification of gynecology.

Genitourinary syndrome of menopause (GSM) is a physiological disorder caused by reduced levels of oestrogen in menopausal women. Gradually, its symptoms worsen with age and prolonged menopausal status, which gravely impacts the quality of life as well as the physical and mental health of the patients. In this regard, optical coherence tomography (OCT) system effectively reduces the patient's burden in clinical diagnosis with its noncontact, noninvasive tomographic imaging process.

Decoding the origins, spread, and global risks of mcr-9 gene.

Background: The global spread of the plasmid-mediated mcr (mobilized colistin resistance) gene family presents a significant threat to the efficacy of colistin, a last-line defense against numerous Gram-negative pathogens. The mcr-9 is the second most prevalent variant after mcr-1.

Methods: A dataset of 698 mcr-9-positive isolates from 44 countries is compiled.

Tracking intra-species and inter-genus transmission of KPC through global plasmids mining.

Klebsiella pneumoniae carbapenemase (KPC) poses a major public health risk. Understanding its transmission dynamics requires examining the epidemiological features of related plasmids. Our study compiled 15,660 bla-positive isolates globally over the past two decades.

Intelligent water perimeter security event recognition based on NAM-MAE and distributed optic fiber acoustic sensing system.

Distributed optical acoustic sensing (DAS) based on phase-sensitive optical time-domain reflectometry can realize the distributed monitoring of multi-point disturbances along an optical fiber, thus making it suitable for water perimeter security applications. However, owing to the complex environment and the production of various noises by the system, continuous and effective recognition of disturbance signals becomes difficult. In this study, we propose a Noise Adaptive Mask-Masked Autoencoders (NAM-MAE) algorithm based on the novel mask mode of a Masked Autoencoders (MAE) and applies it to the intelligent event recognition in DAS.

RVM-GSM: Classification of OCT Images of Genitourinary Syndrome of Menopause Based on Integrated Model of Local-Global Information Pattern.

Genitourinary syndrome of menopause (GSM) is a group of syndromes, including atrophy of the reproductive tract and urinary tract, and sexual dysfunction, caused by decreased levels of hormones, such as estrogen, in women during the transition to, or late stage of, menopause. GSM symptoms can gradually become severe with age and menopausal time, seriously affecting the safety, and physical and mental health, of patients. Optical coherence tomography (OCT) systems can obtain images similar to "optical slices" in a non-destructive manner.

CTS-Net: A Segmentation Network for Glaucoma Optical Coherence Tomography Retinal Layer Images.

Optical Coherence Tomography (OCT) technology is essential to obtain glaucoma diagnostic data non-invasively and rapidly. Early diagnosis of glaucoma can be achieved by analyzing the thickness and shape of retinal layers. Accurate retinal layer segmentation assists ophthalmologists in improving the efficiency of disease diagnosis.

CroReLU: Cross-Crossing Space-Based Visual Activation Function for Lung Cancer Pathology Image Recognition.

Lung cancer is one of the most common malignant tumors in human beings. It is highly fatal, as its early symptoms are not obvious. In clinical medicine, physicians rely on the information provided by pathology tests as an important reference for the final diagnosis of many diseases.

Study on timing sequence control fracture blasting excavation of deep rock masses with filled joints.

During the blasting excavation of deep underground caverns, the effects of the structural surface on crack propagation are usually considered in addition to the clamping effects of high in situ stress. Based on the notched borehole and timing sequence control (TSC) fracture blasting method, this paper studies the effects of different borehole shapes on the degree of damage of the surrounding rock and profile flatness of the rock anchor beams and the effects of different filled joint characteristics on the blasting crack propagation rules. The results show that the damage depth of the surrounding rocks by round hole smooth blasting is approximately twice that by notched hole smooth blasting, by which the profile formed is flatter.

Predictors of strain for Canadian caregivers seeking service navigation for their youth with mental health and/or addictions issues.

Caring for youth with mental health and/or addictions (MHA) concerns is associated with caregiver strain, which may lead to negative consequences for youth and their caregivers. These consequences may be mitigated by caregivers and/or youth receiving assistance in navigating the healthcare system. Understanding what factors are associated with caregiver strain may be important in developing and implementing navigation services for such families; nonetheless, limited evidence currently exists regarding the predictors of strain in caregivers seeking navigation support.

An Ontology-Independent Representation Learning for Similar Disease Detection Based on Multi-Layer Similarity Network.

To identify similar diseases has significant implications for revealing the etiology and pathogenesis of diseases and further research in the domain of biomedicine. Currently, most methods for the measurement of disease similarity utilize either associations of ontological disease concepts or functional interactions between disease-related genes. These methods are heavily dependent on the ontology, which are not always available, and the selection of datasets.