Publications by authors named "Kaitlyn Larsen"
Mol Cell Neurosci
September 2016
Article Synopsis
- 14-3-3 proteins are important molecular chaperones that help regulate various cellular functions, and are linked to neurodegenerative diseases and alcohol use disorders.
- Five out of seven 14-3-3 transcripts were significantly down-regulated after chronic ethanol treatment in HEK293T cells, mirroring changes observed in the brains of human alcoholics, while one transcript increased in expression.
- Following miRNA transfection, only miR-203 down-regulated 14-3-3θ, but miR-7 and miR-144 led to upregulation of other isoforms, suggesting miRNA may affect neurotransmission and cellular balance in the context of alcohol exposure.
