Publications by authors named "Kais Chaabene"
Article Synopsis
- - Peripartum cardiomyopathy (PPCM) is a rare and serious heart condition often occurring during or after pregnancy; this study assessed its outcomes in North Africa over a 12-year period from 2010 to 2022.
- - Out of 27 PPCM patients studied, most presented symptoms like severe dyspnea and had a low average heart function measurement (LVEF of 30%); complications included pulmonary edema (85%) and the need for ECMO support in two patients.
- - The follow-up revealed that 67% of patients showed recovery in heart function, but the overall mortality rate was 15%, with significant mortality associated with factors like past pregnancies and poor prenatal care.
Background: Polycystic Ovary Syndrome (PCOS) is the most frequent endocrine disorder that affects reproductive-age women with important long-term health implications. As such, the anti-Müllerian hormone (AMH) was proposed as a helpful test to identify women with PCOS. The aim of this study was to determine an AMH cut-off value for the diagnosis of PCOS.
View Article and Find Full Text PDFBackground: Previous studies have shown that poor prognostic indicators of inflammatory breast cancer (IBC) include younger age at diagnosis, poorer tumor grade, negative estrogen receptor, lesser degree of pathological response in the breast and lymph nodes.
Methods: This is a retrospective study conducted over a period of 12 years between January 2008 and December 2019 at the medical oncology department at Habib Bourguiba University Hospital in Sfax. We included in this study women with confirmed IBC.
Background: Severe valvular heart disease, especially stenosis, is a contraindication for conception according to the World Health Organization. This is still encountered in countries with a high rheumatic fever prevalence. The objective of this study was to determine predictors of maternal cardiac, obstetric and neonatal complications in pregnant women with severe valve disease.
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- The COVID-19 pandemic presents a challenge for Reproductive Medicine, which is typically considered a non-emergency activity, except for cases involving cancer-related fertility preservation.
- Leading fertility organizations like ASRM and ESHRE advised halting new patient intakes and suggested continuing only existing IVF cycles with a preference for Freeze-all strategies.
- Recent developments and new data have emerged, prompting a need to revise previously established recommendations in Tunisia, reflecting the changes in the situation.
Steroid cell tumors (SCTs) (not otherwise specified (NOS)) are rare sex cord-stromal tumors of the ovary. These are associated with hormonal disturbances resulting in menstrual bleeding patterns and androgenic effects. We report the case of a 36-year-old female presented with hirsutism, signs of virilization, and elevated androgen levels.
View Article and Find Full Text PDFThis work aimed to explore the expression pattern of circulating miR-199a-3p, miR-21-5p and miR-let7i-3p in infertile women with dysregulated AMH levels. Quantitative real-time PCR was used to measure miR-199a-3p, miR-21-5p, and miR-let7i-3p expression levels in 60 plasma samples of infertile women with low or high AMH levels. Bioinformatic analyses for microRNAs predicting target genes and molecular pathways were performed according to gene ontology (GO) analysis and KEGG pathways.
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- Miscarriage is a common pregnancy issue, and this study aimed to explore how zoonotic bacteria and genital pathogens might be linked to miscarriages in women.
- The research involved analyzing samples from 132 women with miscarriages and 54 women with healthy pregnancies to detect various bacteria through culture and real-time PCR.
- Results indicated that certain pathogens like Chlamydia trachomatis and Mycoplasma hominis were more prevalent in women who experienced miscarriages, but further research is needed to fully understand these connections and the high seroprevalence of Waddlia chondrophila in early miscarriages.
Metastases of ovarian carcinoma to the breast are uncommon. The incidence of ovarian metastasis to the breast ranges from 0.5% to 1.
View Article and Find Full Text PDFObjective: To describe for the first time the epidemiologic and clinico-pathologic characteristics of vulvar cancer in Tunisia.
Design: Two parts are distinguished in this study: Part1: Multicentric retrospective study about the characteristics of all cancer cases diagnosed during a 17-years period (January 1998-December 2014) in three departments of Gynecology and Obstetrics: one in south Tunisia and two in the capital. Part 2: To determine the Incidence trend of invasive vulvar cancer in North Tunisia 1994-2009, on the basis of North Cancer Registry of Tunisia.
Article Synopsis
- The study examined how breast cancer treatment affects sexual life among Tunisian women, focusing on changes in sexuality and the impact of demographic and clinical factors.
- Researchers evaluated 50 women in remission using specific scales for sexuality and emotional health, revealing low sexual functioning and satisfaction scores.
- Significant findings indicated that menopausal status and partner’s sexual difficulties affected satisfaction levels, while anxiety and depression were prevalent among participants, highlighting the need for psychological support in their treatment.
The factor V deficiency is a very rare hereditary disease of the coagulation, which is accompanied by a high hemorrhagic risk in the event of delivery and in the post-partum. We report the case of a woman having a factor V deficiency which had a pregnancy, and which gave birth by Cesarean, as replacement therapy we proposed the transfusion of 20 mL/kg of fresh frozen plasma before surgery and of 5 mL/kg by 12 h during 7 days in post-partum, this attitude allowed to avoid the hemorrhagic complications.
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