Association Between Platelet Levels and 28-Day Mortality in Patients With Sepsis: A Retrospective Analysis of a Large Clinical Database MIMIC-IV.

Background: This research focused on evaluating the correlation between platelet count and sepsis prognosis, and even the dose-response relationship, in a cohort of American adults.

Method: Platelet counts were recorded retrospectively after hospitalization for patients admitted to Beth Israel Deaconess Medical Center's intensive care unit between 2008 and 2019. On admission to the intensive care unit, sepsis patients were divided into four categories based on platelet counts (very low < 50 × 10/L, intermediate-low 50 × 10-100 × 10/L, low 100 × 10-150 × 10/L, and normal ≥ 150 × 10/L).

Correlation of AIF-1 Expression with Immune and Clinical Features in 1270 Glioma Samples.

AIF-1 gene is surrounded by the genes involved in the inflammatory response and located in the major histocompatibility complex (MHC) class III genomic region. It has been found that microglial cells expressed the AIF-1 gene during all stages of mice brain development. However, the role of AIF-1 remains unclear in glioma.

Relationship between Lp-PLA2 and in-stent restenosis after coronary stenting: a 3-year follow-up study.

Background And Aims: Coronary in-stent restenosis (ISR) is an important complication of percutaneous coronary intervention (PCI). However, the relationship between lipoprotein associated phospholipase A2 (Lp-PLA2) level and ISR after PCI is rarely reported. This study aims to explore the relationship between Lp-PLA2 and the occurrence of ISR at post-PCI and its predictive value for ISR.

Nanostructured High-Performance Thin-Film Transistors and Phototransistors Fabricated by a High-Yield and Versatile Near-Field Nanolithography Strategy.

Thin-film transistors (TFTs) and field-effect transistors (FETs) are basic units to build functional electronic circuits and investigate transport physics. In conventional TFTs or FETs, performance in terms of current level, on-off ratio, and the sensitivity of detection is limited by homogeneous semiconducting layers. In this paper, we develop TFTs with submicron heterostructures by using a strategy based on near-field photolithography.

Blood oxygenation changes resulting from subthreshold high frequency repetitive transcranial magnetic stimulation.

Effects of high frequency repetitive transcranial magnetic stimulation (rTMS) with a subthreshold intensity on hemodynamic response in brain cortices (both motor and prefrontal cortices) was investigated using the functional near infrared spectroscopy (fNIRS) technique. FNIRS signals of the motor and prefrontal cortices were acquired in healthy volunteers (n=7) at rest and during rTMS intervention. A significant reduction in oxygenated hemoglobin (HbO) concentration during the entire stimulation process was observed from both motor and prefrontal cortices.