Publications by authors named "Kaio Eduardo Buglio"
Antibacterial profile and antiproliferative activities over human tumor cells of new silver(I) complexes containing two distinct trifluoromethyl uracil isomers.
Gabriele de Menezes Pereira Julia H Bormio Nunes Vinicius Souza Macedo Douglas Henrique Pereira Kaio Eduardo Buglio
J Inorg Biochem
January 2025
Article Synopsis
- New silver(I) complexes of 5-(trifluoromethyl)uracil (5TFMU) and 6-(trifluoromethyl)uracil (6TFMU) were synthesized and characterized for their antibacterial and antiproliferative activities.
- Structural analyses indicated that 5TFMU acts as a tridentate ligand forming distinct coordination environments, while 6TFMU forms a more complex polymeric structure with multiple coordination sites.
- Both complexes showed modest antibacterial activity, with Ag-6TFMU displaying better efficacy against certain tumor cells, particularly in prostate and kidney cell lines, while Ag-5TFMU had a broader activity profile against various tumor cells but lacked selectivity.
Cytoprotective effect of (Bonpl.) L.G. Lohmann extract associated with geranylgeraniol enriched-fraction from L. on epithelial cells treated with bisphosphonate.
Rogério José Machado Júnior Júlia C Camilli Rosanna Tarkany Basting Patrícia Maria Wiziacki Zago Ilza Maria de Oliveira Sousa Kaio Eduardo Buglio
Nat Prod Res
October 2022
Bisphosphonates are drugs used to treat bone disorders. The chronic use of bisphosphonates is associated with the occurrence of medication-related osteonecrosis of the jaw (MRONJ). Previous data reported the positive effects of Geranylgeraniol on different cell types treated with Bisphosphonates.
View Article and Find Full Text PDFMart. (açai) is a native palm from the Amazon region. There are various chemical constituents of açai with bioactive properties.
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