Publications by authors named "Kaining Yao"
Article Synopsis
- The study developed a fully automatic iterative planning (AIP) system for generating advanced radiation therapy plans for patients with locally advanced rectal cancer.
- The AIP system automates the planning process via a web-based interface and uses advanced algorithms to efficiently optimize treatment plans, showing promising results in terms of planning time and quality.
- Comparison between automatic and manual plans demonstrated improved conformity and sparing of organs at risk, while maintaining consistent quality across automatic plans, with a notably quicker overall planning timeframe.
Article Synopsis
- The study examines the health risks associated with repeated cone-beam CT (CBCT) scans used in image-guided radiotherapy (IGRT) and proposes a virtual clinical trial to assess low-dose scanning methods.
- A total of 71 patients were virtually enrolled, with reduced projection numbers simulating low-dose scans, while measuring contrast-to-noise ratio (CNR) and registration errors.
- Results showed CNR values decreased with reduced projections, but registration errors remained statistically insignificant, suggesting a need for further validation on optimizing CBCT imaging doses.
Article Synopsis
- This study focuses on improving a commercial deep learning auto-segmentation model for rectal cancer radiotherapy by using a method called localized fine-tuning (LFT), addressing the issue of performance decline when models are used in real clinical settings.
- Researchers evaluated the model's effectiveness by dividing 120 rectal cancer patients into training and validation datasets, and they compared the LFT model's performance against the vendor-provided pretrained model (VPM) using various accuracy metrics.
- Results showed that LFT significantly enhanced the accuracy for marking clinical target volumes, especially improving the segmentation of complex structures, with no performance degradation noted when tested in different clinical environments.
Purpose: To propose a straightforward and time-efficient quality assurance (QA) approach of beam time delay for respiratory-gated radiotherapy and validate the proposed method on typical respiratory gating systems, Catalyst™ and AlignRT™.
Methods: The QA apparatus was composed of a motion platform and a Winston-Lutz cube phantom (WL3) embedded with metal balls. The apparatus was first scanned in CT-Sim and two types of QA plans specific for beam on and beam off time delay, respectively, were designed.
. This study proposes and evaluates a new figure of merit (FOMn) for dose optimization of Dual-energy cone-beam CT (DE-CBCT) scanning protocols based on size-dependent modeling of radiation dose and multi-scale image quality..
View Article and Find Full Text PDFPurpose: To propose a specific surface guided stereotactic radiotherapy (SRT) treatment procedure with open-face mask immobilization and evaluate the initial clinical experience in improving setup accuracy.
Methods And Materials: The treatment records of 48 SRT patients with head lesions were retrospectively analyzed. For each patient, head immobilization was achieved with a double-shell open-face mask.
Background: Accurate target volume delineation is the premise for the implementation of precise radiotherapy. Inadequate target volume delineation may diminish tumor control or increase toxicity. Although several clinical target volume (CTV) delineation guidelines for rectal cancer have been published in recent years, significant interobserver variation (IOV) in CTV delineation still exists among radiation oncologists.
View Article and Find Full Text PDFObjective: To develop and evaluate a practical automatic treatment planning method for intensity-modulated radiation therapy (IMRT) in cervical cancer cases.
Methods: A novel algorithm named as Optimization Objectives Tree Search Algorithm (OOTSA) was proposed to emulate the planning optimization process and achieve a progressively improving IMRT plan, based on the Eclipse Scripting Application Programming Interface (ESAPI). 30 previously treated cervical cancer cases were selected from the clinical database and comparison was made between the OOTSA-generated plans and clinical treated plans and RapidPlan-based (RP) plans.
Purpose: The aim of this study is to compare the dosimetric and mechanical accuracy of Volumetric Modulation Arc Therapy (VMAT) delivery on the Halcyon, a recent ring-shaped Treatment Delivery System (TDS) featuring fast rotating gantry, with a conventional C-arm Linac.
Methods: The comparison was performed via log file analysis, where mechanical parameters of related components was extracted. 480 and 3951 VMAT log files of clinically delivered fractions from a Halcyon and a TrueBeam Linac were analyzed respectively.