Publications by authors named "Kainan Liao"

Article Synopsis
  • * High glucose causes mitochondrial damage, apoptosis, and cellular senescence in renal tubular epithelial cells, but the extent to which senescence worsens these impairments in DN is still unclear.
  • * The study reveals that high glucose affects mitochondrial function, cellular senescence, and apoptosis by increasing cytokine secretion, reactive oxygen species, and intracellular calcium, while the anti-aging agent resveratrol can mitigate these harmful effects.
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A ginseng polysaccharide was extracted, purified, and modified by nitric acid-selenious acid (HNO-HSeO) method to yield one selenylation-modified polysaccharide (sGP). We reported for the first time the anticancer potential of sGP on the human promyelocytic leukemia HL-60 cell line and evaluated its relevant underlying mechanism. Our results showed that sGP markedly inhibited the growth of HL-60 cells via induction of apoptosis.

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