Publications by authors named "Kailee Yap"
Article Synopsis
- The research included a review of 42 patients' medical charts, revealing that 93% exhibited eye problems, with issues like optic nerve/chorioretinal colobomas being the most common.
- The study noted variability in eye conditions with no clear link to specific genetic variants, highlighting the need for more research to understand these associations better.
Nucleus accumbens-associated protein 1 (NAC1), encoded by the NACC1 gene, is a transcription co-regulator that plays a multifaceted role in promoting tumorigenesis. However, the NAC1-regulated transcriptome has not been comprehensively defined. In this study, we compared the global gene expression profiles of NAC1-overexpressing SKOV3 ovarian cancer cells and NAC1-knockdown SKOV3 cells.
View Article and Find Full Text PDFBackground: Ovarian cancer is one of the most lethal types of female malignancy. Although most patients are initially responsive to platinum-based chemotherapy, almost all develop recurrent chemoresistant tumors and succumb to their diseases. Elucidating the pathogenesis underlying drug resistance is fundamental to the development of new therapeutics, leading to improved clinical outcomes in these patients.
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