Porous structure design and mechanical behavior analysis based on TPMS for customized root analogue implant.

Compared with the traditional dental implant with screw structure, the root analogue implant (RAI) is customized to fit with the wall of the alveolar bone, which helps to accelerate the clinical implantation process. However, a solid RAI made of Ti6Al4V material has a much higher Young's modulus than the surrounding bone tissue, which can cause a stress shielding effect and thereby lead to implant failure. Also, a solid RAI is not conducive to the growth of osteoblasts.

Biological and mechanical property analysis for designed heterogeneous porous scaffolds based on the refined TPMS.

For tissue engineering (TE), triply periodic minimal surfaces (TPMSs) have received widespread application, as they produce smooth surfaces and pore interconnectivity, which can satisfy the biological/mechanical requirements and efficiently construct many complex bone scaffolds. To control the microstructure of the scaffold and mimic the anisotropy of native tissue, a design approach for heterogeneous porous scaffolds is proposed in this paper. It is carried out by discretizing the original model using the conformal refinement of an all-hexahedral mesh and mapping the TPMS units to the mesh elements with the help of a shape function.