Publications by authors named "Kailas K Mali"

Article Synopsis
  • This study investigated the use of citric acid-crosslinked hydroxyethyl tamarind gum (HETG) hydrogel films as drug delivery systems.
  • The modification of tamarind gum aimed to enhance its properties like solubility and swelling, leading to effective drug loading and controlled release mechanisms.
  • Characterization showed these films possess antimicrobial properties and biocompatibility, indicating their potential for wound healing applications.
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The aim of present work was to synthesize and characterize carboxymethyl tamarind gum-polyvinyl alcohol (CMTG-PVA) hydrogel films using citric acid (CA) as a crosslinker. Hydrogel films were prepared by solvent casting technique. The films were evaluated for total carboxyl content (TCC), tensile strength, protein adsorption, permeability properties, hemocompatibility, swellability, moxifloxacin (MFX) loading and release, in-vivo wound healing activity and characterized using instrumental techniques.

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Objectives: The present study aimed to evaluate the nootropic activity of in rats.

Materials And Methods: Methanolic extract of was used to evaluate nootropic activity, piracetam (200 mg/kg, i.p.

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In present work, carboxymethylcellulose (CMC) - polyethylene glycol (PEG) hydrogel films were prepared using citric acid as a non-toxic crosslinking agent, for the controlled delivery of model hydrophobic drug (ketoconazole). The carboxyl content of the hydrogel films were determined by acid-base titration. The films were characterized by solid state C NMR, ATR-FTIR, TGA and DSC, and evaluated for swelling behavior, drug loading, drug release, hemocompatibility, in vitro cytotoxicity and implantation test.

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The objective of this study was to synthesize and characterize citric acid crosslinked carboxymethyl tamarind gum (CMTG) hydrogels films. The hydrogel films were characterized by Attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy, solid state C-nuclear magnetic resonance (C NMR) spectroscopy and differential scanning calorimeter (DSC). The prepared hydrogel films were evaluated for the carboxyl content and swelling ratio.

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Background: The existing conventional liver function tests (LFTs) are indirect, inferior and have limited prognostic value. Therefore, the monoethylglycinexylidide (MEGX) test, which provides a direct measure of the actual functional state of the liver, is proposed as a real-time liver function test. The objective of this study was to assess the prognostic value of the MEGX test in cirrhosis by comparing it with Child-Turcotte-Pugh (CTP), the Mayo end stage liver disease (MELD) and discriminant function (DF) scores.

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