Gene Family Revealed Genetic Variations in Autotetraploid .

The gene family encoded transcription factors that played key roles in developmental processes in vertebrates. To further understand the evolutionary fate of the gene family in teleosts, the genes were comprehensively characterized in fish of different ploidy levels, including blunt snout bream (2n = 48, , BSB), goldfish (2n = 100, red var., 2nRCC), and autotetraploid (4n = 200, 4nRCC).

Comparative analyses of the Sox9a-Amh-Cyp19a1a regulatory Cascade in Autotetraploid fish and its diploid parent.

Background: Autotetraploid Carassius auratus (4nRCC, 4n = 200, RRRR) was derived from the whole genome duplication of diploid red crucian carp (Carassius auratus red var.) (2nRCC, 2n = 100, RR). To investigate the genetic effects of tetraploidization, we analyzed DNA variation, epigenetic modification and gene expression changes in the Sox9a-Amh-Cyp19a1a regulatory cascade between 4nRCC and 2nRCC.