Three-axis closed-loop optically pumped magnetometer operated in the SERF regime.

We propose a three-axis closed-loop optically pumped magnetometer with high sensitivity. The closed-loop magnetometer has a three-axis sensitivity of approximately 30 fT/Hz using two orthogonal laser beams for pumping and probing the alkali metal atoms. In the closed-loop mode, the dynamic range is improved from ±5 nT to ±150 nT.

Three-dimensional assessment of virtual bracket removal for orthodontic retainers: A prospective clinical study.

Introduction: Computer-aided design and manufacturing of orthodontic retainers from digitally debonded models can be used to facilitate same-day delivery. The purpose of this prospective clinical study was to validate a novel technique for virtual bracket removal (VBR) in-office, comparing the accuracy with 2 orthodontic laboratories that use VBR for retainer fabrication in the digital workflow.

Methods: The sample consisted of 40 intraoral scans of 20 patients.

The biocompatibility and mechanical properties of plasma sprayed zirconia coated abutment.

Purpose: The aim of this study was to evaluate the clinical performance and reliability of plasma sprayed nanostructured zirconia (NSZ) coating.

Materials And Methods: This study consisted of three areas of analysis: (1) Mechanical property: surface roughness of NSZ coating and bond strength between NSZ coating and titanium specimens were measured, and the microstructure of bonding interface was also observed by scanning election microscope (SEM). (2) Biocompatibility: hemolysis tests, cell proliferation tests, and rat subcutaneous implant test were conducted to evaluate the biocompatibility of NSZ coating.

Evaluating the treatment effectiveness and efficiency of Carriere Distalizer: a cephalometric and study model comparison of Class II appliances.

Background: The purpose of this study was to evaluate the treatment effectiveness of Carriere Distalizer in comparison to Class II intermaxillary elastics and Forsus.

Methods: Three groups of patients treated with Class II intermaxillary elastics (n = 18), Carriere Distalizer (n = 18), and Forsus appliance (n = 18) were collected from three private orthodontic practices. Inclusion criteria were as follows: (1) 10-14 years old of start age with permanent dentition, (2) no history of previous orthodontic treatment, (3) complete pre- and post-treatment records, (4) dental Class II division 1 (end-to-end or more), (5) no pre-treatment transverse discrepancy, (6) non-extraction treatment plan, and (7) Class I post-treatment occlusal relationship.

MicroRNA-29a-3p enhances dental implant osseointegration of hyperlipidemic rats via suppressing dishevelled 2 and frizzled 4.

Background: Fine osseointegration is the basis of long-term survival of implant. In our previous study, we observed a strong correlation between hyperlipidemia and compromised osseointegration. MicroRNA-29a-3p (miR-29a-3p) has been discovered to participate in bone marrow mesenchymal stem cells (BMSCs) differentiation.

Efficacy of sodium bicarbonate buffered versus non-buffered lidocaine with epinephrine in inferior alveolar nerve block: A meta-analysis.

Introduction: This systematic review evaluated the use of buffered versus non-buffered lidocaine to increase the efficacy of inferior alveolar nerve block (IANB).

Materials And Methods: Randomized, double-blinded studies from PubMed, Web of Science, Cochrane Library, Embase, and ProQuest were identified. Two of the authors assessed the studies for risk of bias.

Application of Plasma Sprayed Zirconia Coating in Dental Implant: Study in Implant.

The aim was to investigate the osseointegration of a novel coating-plasma-sprayed nanostructured zirconia (NSZ) in dental implant. Nanostructured zirconia coating on non-thread titanium implant was prepared by plasma spraying, the implant surface morphology, surface roughness and wettability were measured. In vivo, nanostructured zirconia-coated implants were inserted in rabbit tibia and animals were respectively sacrificed at 2, 4, 8 and 12 weeks after implantation.

Bicarbonate Transport During Enamel Maturation.

Amelogenesis (tooth enamel formation) is a biomineralization process consisting primarily of two stages (secretory stage and maturation stage) with unique features. During the secretory stage, the inner epithelium of the enamel organ (i.e.

Multiple Calcium Export Exchangers and Pumps Are a Prominent Feature of Enamel Organ Cells.

Calcium export is a key function for the enamel organ during all stages of amelogenesis. Expression of a number of ATPase calcium transporting, plasma membrane genes (ATP2B1-4/PMCA1-4), solute carrier SLC8A genes (sodium/calcium exchanger or NCX1-3), and SLC24A gene family members (sodium/potassium/calcium exchanger or NCKX1-6) have been investigated in the developing enamel organ in earlier studies. This paper reviews the calcium export pathways that have been described and adds novel insights to the spatiotemporal expression patterns of PMCA1, PMCA4, and NCKX3 during amelogenesis.

Deletion of and Delays Enamel Mineralization in Mice.

Amelogenesis features two major developmental stages-secretory and maturation. During maturation stage, hydroxyapatite deposition and matrix turnover require delicate pH regulatory mechanisms mediated by multiple ion transporters. Several members of the Slc26 gene family (, which exhibit bicarbonate transport activities, have been suggested by previous studies to be involved in maturation-stage amelogenesis, especially the key process of pH regulation.

MiR-153 Regulates Amelogenesis by Targeting Endocytotic and Endosomal/lysosomal Pathways-Novel Insight into the Origins of Enamel Pathologies.

Amelogenesis imperfecta (AI) is group of inherited disorders resulting in enamel pathologies. The involvement of epigenetic regulation in the pathogenesis of AI is yet to be clarified due to a lack of knowledge about amelogenesis. Our previous genome-wide microRNA and mRNA transcriptome analyses suggest a key role for miR-153 in endosome/lysosome-related pathways during amelogenesis.

SLC26A Gene Family Participate in pH Regulation during Enamel Maturation.

The bicarbonate transport activities of Slc26a1, Slc26a6 and Slc26a7 are essential to physiological processes in multiple organs. Although mutations of Slc26a1, Slc26a6 and Slc26a7 have not been linked to any human diseases, disruption of Slc26a1, Slc26a6 or Slc26a7 expression in animals causes severe dysregulation of acid-base balance and disorder of anion homeostasis. Amelogenesis, especially the enamel formation during maturation stage, requires complex pH regulation mechanisms based on ion transport.

Genome-wide analysis of miRNA and mRNA transcriptomes during amelogenesis.

Background: In the rodent incisor during amelogenesis, as ameloblast cells transition from secretory stage to maturation stage, their morphology and transcriptome profiles change dramatically. Prior whole genome transcriptome analysis has given a broad picture of the molecular activities dominating both stages of amelogenesis, but this type of analysis has not included miRNA transcript profiling. In this study, we set out to document which miRNAs and corresponding target genes change significantly as ameloblasts transition from secretory- to maturation-stage amelogenesis.

[Evaluation of the efficiency of different instrumentation for root canal retreatment using micro-computed tomography].

Objective: To establish the three-dimensional model of human permanent premolars based on Micro-computed tomography (Micro-CT) data, and evaluate the efficiency quantitatively of two different instrumentations for root canal retreatment.

Methods: Forty extracted permanent premolars for the reason of orthodontic treatment were collected, prepared by using ProTaper Ni-Ti files and filled by cold gutta pertscha lateral condensation technique. The subjects were scanned by Micro-CT.

The experimental research on two-generation BLB dental implants - part I: surface modification and osseointegration.

Objective: The study was designed to evaluate the comparative effect of osseointegration induced by the dental implants of Beijing Leiden Biomaterial (BLB) and BLBIII.

Materials And Methods: The surface properties ofBLBI and BLBIII were studied through thermal field-scanning electron microscopy, energy-dispersive X-ray spectroscopy (EDS) and optical profilometer. A total of 36 BLBI and BLBIII implants, with each of the two groups possessing 18, were randomly implanted into the extraction fossa of the mandibular premolar areas of six Beagles.