Synopsis of recent research by authors named "Kaichuan Zhu"
- Kaichuan Zhu's research primarily focuses on the underlying mechanisms of neurodegenerative diseases, particularly Alzheimer's disease (AD), explored through various experimental models including mouse and primate models to understand genetic, molecular, and synaptic alterations associated with AD.
- Recent findings indicate significant roles for immune molecules, such as TREM2, and the impact of amyloid-beta on synaptic function and plasticity, highlighting their contributions to both glioma and Alzheimer's disease pathology.
- Zhu's studies employ advanced techniques like CRISPR/Cas9 gene editing and detailed biochemical analyses to investigate how specific mutations and pharmacological interventions influence neurodegeneration, synapse maintenance, and cognitive implications in animal models.
