Publications by authors named "Kaicen Zhu"

Epilepsy is a heterogenous group of disorders defined by recurrent seizure activity due to abnormal synchronized activity of neurons. A growing number of epilepsy cases are believed to be caused by genetic factors and copy number variants (CNV) contribute to up to 5% of epilepsy cases. However, CNVs in epilepsy are usually large deletions or duplications involving multiple neurodevelopmental genes.

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Article Synopsis
  • Comprehensive analysis of pediatric low-grade gliomas (PLGGs) identified five distinct subgroups based on factors like tumor location and lymphocyte infiltration.
  • Some subgroups showed associations with worse progression-free survival, particularly those with high lymphocyte presence.
  • Despite the low confidence of current methylation classifiers in many cases, combining histopathological and molecular data led to better risk stratification of certain tumor types.
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Background: This study evaluated patient-reported outcomes in patients undergoing primary total hip arthroplasty with a polyethylene liner to determine the influence of cup orientation and other variables on patient-reported outcomes.

Methods: A total of 477 cases were prospectively monitored through average 4.7 years follow-up.

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This study examined functional properties and biocompatibility of glutaraldehyde-fixed bovine articular cartilage over several weeks of incubation at body temperature to investigate its potential use as a resurfacing material in joint arthroplasty. In the first experiment, treated cartilage disks were fixed using 0.02, 0.

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Quantitative measurements of cartilage wear have been challenging, with no method having yet emerged as a standard. This study tested the hypothesis that latest-generation particle analyzers are capable of detecting cartilage wear debris generated during in vitro loading experiments that last 24 h or less, by producing measurable content significantly above background noise levels otherwise undetectable through standard biochemical assays. Immature bovine cartilage disks (4 mm diameter, 1.

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