Experiences and barriers with home bladder manometry in the pediatric neurogenic bladder population: A qualitative study.

Background: Patients with neurogenic bladder are at risk of developing renal deterioration secondary to increased intravesical pressures. To date, urodynamics is the gold standard test to properly assess bladder dynamics. Home bladder manometry is a low-cost and simple method to evaluate bladder pressures and volumes during clean intermittent catheterization (CIC).

The conundrum of high-grade hydronephrosis with non-obstructive drainage on diuretic renography.

Background: Patients with high grade hydronephrosis (HN) and non-obstructive drainage on mercaptoacetyltriglycine (MAG-3) diuretic renography (renal scans) can pose a dilemma for clinicians. Some patients may progress and require pyeloplasty; however, more clarity is needed on outcomes among these patients.

Objective: Our primary objective was to predict which patients with high-grade HN and non-obstructive renal scan, (defined as T ½ time <20 min) would experience resolution of HN.

The double-face onlay-tube-onlay transverse preputial flap: An advantageous alternative to the two-stage hypospadias repair?

Objective: To compare the surgical outcomes and complications of boys who underwent double-face onlay-tube-onlay transverse preputial island flap (DFOTO) one-stage repair vs. two-stage repair for proximal hypospadias.

Study Design: Males with proximal hypospadias who underwent DFOTO or two-stage repair at a single institution from 2008 to 2021 were identified.

Conformal Conductive Features on Curvilinear Surfaces with Self-Assembled Silver Nanoplate Thin Films.

In this study, a water transfer method was developed to fabricate conducive thin-film patterns on 3D curvilinear surfaces. Crystalline silver nanoplates (AgNPLs) with a dimension of 700 nm and a thickness of 35 nm were suspended in ethanol with an anionic surfactant, sodium dodecyl sulfate, to improve the suspension stability. The prepared AgNPL suspension was then spread over the water surface via the Langmuir-Blodgett approach to generate a self-assembled thin film.

Association Between Serum Total IgE Levels and Clinical Response to Omalizumab for Chronic Spontaneous Urticaria: A Systematic Review and Meta-Analysis.

Background: Omalizumab is the only biological agent approved for patients with chronic spontaneous urticaria (CSU), but no biomarker is well established for predicting clinical response to omalizumab.

Objective: We aimed to determine the association between baseline total serum IgE levels and the effects of omalizumab in patients with CSU.

Methods: PubMed, Web of Science, Scopus, and Cochrane Library were systematically searched for relevant studies from inception to August 23, 2022.

Enhancing Stability of High-Concentration β-Tricalcium Phosphate Suspension for Biomedical Application.

We propose a novel process to efficiently prepare highly dispersed and stable Tricalcium Phosphate (β-TCP) suspensions. TCP is coupled with a polymer to enhance its brittleness to be used as an artificial hard tissue. A high solid fraction of β-TCP is mixed with the polymer in order to improve the mechanical strength of the prepared material.

Recurrent ventral curvature after corporoplasty with tunica vaginalis flap.

Introduction And Objective: Optimal means to correct ventral curvature (VC) is debated. Our preferred technique for curvature greater than 45° is corporoplasty using tunica vaginalis flap (TVF). We describe our complications with TVF for ventral lengthening.

Timely orchiopexy by 18 months of age: Are we meeting the standards defined by the 2014 AUA guidelines?

Background: Cryptorchidism is one of the most common reasons for pediatric urology referral and one of the few pediatric urologic conditions in which there are established AUA guidelines that recommend orchiopexy be performed before 18 months of age. While access to timely orchiopexy has been studied previously, there is no current study with data from a national clinical database evaluating timely orchiopexy after the AUA guidelines were published. Additionally, prior studies on delayed orchiopexy may have included patients with an ascended testis, which is a distinct population from those with true undescended testicles.

Single-Layer Acellular Porcine Bladder Matrix as Graft in Corporoplasty for Ventral Curvature in Pediatric Proximal Hypospadias Repair: An Initial Experience.

Background: Single-layer ACell Cytal matrix (ACell Inc, Columbia, MD) is a commercially available, acellular scaffold derived from porcine bladder epithelial basement membrane and tunica propria. We describe our initial experience using Cytal as corporal graft in pediatric patients who underwent correction of ventral curvature in proximal hypospadias repair.

Methods: A retrospective review of a single-institution, 4 surgeon hypospadias database was performed between January 2020 and December 2021.

Home bladder pressure measurements correlate with urodynamic storage pressures and high-grade hydronephrosis in children with spina bifida.

Background: Patients with spina bifida are at risk for developing bladder and renal deterioration secondary to increased bladder storage pressures.

Objectives: To determine the association of home bladder volume and pressure measurements (home manometry) to: 1) detrusor storage pressures on urodynamics (UDS); and 2) the presence of Society of Fetal Urology (SFU) grades 3-4 hydronephrosis on renal bladder ultrasound in patients with spina bifida.

Methods: Data were prospectively collected on patients with spina bifida and neurogenic bladder requiring clean intermittent catheterization.

Continuous antibiotic prophylaxis in isolated prenatal hydronephrosis.

Background: Prenatal hydronephrosis (PNH) is one of the most common congenital anomalies and can increase the risk of developing a urinary tract infection (UTI) in the first two years of life. Continuous antibiotic prophylaxis (CAP) has been recommended empirically to prevent UTI in children with PNH, but its use has been controversial.

Objective: We describe the incidence of UTI in children with isolated PNH of the renal pelvis without ureteral dilation.

Risk of ischaemic heart diseases and stroke in behçet disease: A systematic review and meta-analysis.

Background: Behçet disease (BD) is a systemic vasculitis. In addition to the mucocutaneous lesions, the vascular injury of pathophysiology in BD is theoretically correlated with cardiovascular diseases. This study aimed to elucidate the association of BD with ischaemic heart diseases (IHDs) and stroke.

Exploring the mechanical properties of nanometer-thick elastic films through micro-drop impinging on large-area suspended graphene.

In this work, the dependence of effective Young's modulus on the thickness of suspended graphene was confirmed through a drop impingement method. Large area suspended graphene (LSG) layers with a diameter of up to 400 μm and a nanometer thickness were prepared through transferring chemical vapor deposition grown graphene from copper substrates. 4, 8, and 12-layer LSG samples were found to be crumpled yet defect-free.

Risk of urinary tract infection in patients with hydroureter: An analysis from the Society of Fetal Urology Prenatal Hydronephrosis Registry.

Background: Prenatal hydronephrosis is one of the most common anomalies detected on prenatal ultrasonography. Patients with prenatal hydronephrosis and ureteral dilation are at increased risk of urinary tract infection (UTI) and continuous antibiotic prophylaxis (CAP) is recommended. However, current guidelines do not define the minimum ureteral diameter that would be considered a dilated ureter in these patients.

A multicenter study of acute testicular torsion in the time of COVID-19.

Background: Testicular torsion is a surgical emergency, and time to detorsion is imperative for testicular salvage. During the COVID-19 pandemic, patients may delay emergency care due to stay-at-home orders and concern of COVID-19 exposure.

Objective: To assess whether emergency presentation for testicular torsion was delayed during the COVID-19 pandemic, and whether the rate of orchiectomy increased compared to a retrospective period.

Retractable foreskin reduces urinary tract infections in infant boys with vesicoureteral reflux.

Background: Uncircumcised males are at higher risk of urinary tract infection (UTI) in the first year of life and circumcision is recommended as an option for males with vesicoureteral reflux (VUR). Uncircumcised males treated successfully with topical corticosteroid cream have decreased risk of UTI but the role of preputial management has not been explored previously in males with VUR.

Objective: We hypothesized that among uncircumcised boys with VUR, those with retractable foreskin would be at reduced risk of UTI compared to those with non-retractable foreskin.

Development and validation of a bladder trabeculation grading system in pediatric neurogenic bladder.

Bladder trabeculation (BT) is commonly noted on cystogram images of patients with neurogenic bladder (NB). BT is associated with a hostile bladder often requiring prompt, more aggressive management. We aimed to define and validate a reliable grading system for BT severity.