In vitro maturation of oocytes is not a risk factor for adult metabolic syndrome of mouse offspring.

Objective: To evaluate the effect of in vitro maturation (IVM) of oocytes on the serum cholesterol profile, glucose and insulin tolerance, blood pressure, and heart rate of adult mouse offspring.

Study Design: The serum cholesterol profile, glucose and insulin tolerance, blood pressure, and heart rate of adult offspring born from in vitro matured oocytes were compared with those of adult offspring born from in vivo matured oocytes.

Results: Offspring born from in vitro matured oocytes showed a normal serum cholesterol profile.

Effect of vitrification of mouse oocyte on the behavior of adult offspring.

Objective: To evaluate the effect of vitrification of mouse oocytes on the behavior of adult offspring.

Study Design: Oocytes from mice were vitrified, warmed and inseminated, and two-cell embryos were transferred to foster mothers. The behavioral characterization of the offspring was detected by the Morris water maze test, forced swimming test, and elevated plus maze test, and compared to that of offspring from fresh oocytes.