Publications by authors named "Kai-Xiang Chen"
Article Synopsis
- The study focuses on improving the stability and solubility of single-chain T-cell receptors (scTCRs) for therapeutic use, addressing their limitations in research and manufacturing.
- Researchers identified key structural motifs in TCR variable domains and developed a strategy to stabilize scTCRs by modifying specific amino acid residues.
- The optimized scTCRs maintain high binding affinities similar to traditional TCRs, showcasing their potential for enhanced TCR-related therapies.
This study aimed to explore the risk factors for acute myocardial injury (AMI) caused by acute organophosphorus pesticide poisoning (AOPP).The clinical data of 98 patients, who were treated in our hospital due to oral AOPP from April 2013 to April 2017, were retrospectively analyzed. These patients were divided into two groups: AMI group and control group.
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