Publications by authors named "Kai-Wu Xu"
Crohn's disease treatment and memory T-cell subset changes: insights from a case series.
Transl Gastroenterol Hepatol
February 2024
Article Synopsis
- * The study involved eight CD patients treated with anti-inflammatory or immunosuppressive drugs, alongside healthy donors for comparison, and analyzed T cell characteristics using flow cytometry.
- * Results showed significant changes in T cell populations in CD patients, including an increase in CD8 T cells and decreased production of crucial cytokines like IFN-γ by memory T cells, indicating altered immune responses post-treatment.
XRCC2 has been shown to increase the radioresistance of some cancers. Here, XRCC2 expression was investigated as a predictor of preoperative radiotherapy (PRT) treatment response in locally advanced rectal cancer (LARC). XRCC2 was found to be overexpressed in rectal cancer tissues resected from patients who underwent surgery without PRT.
View Article and Find Full Text PDFX-ray repair cross-complementing group 1 (XRCC1) plays a key role in DNA repair, genetic instability, and tumorigenesis. The XRCC1 R399Q polymorphism has been reported in some studies to influence the risk of colorectal cancer (CRC), though this remains controversial. We performed a meta-analysis to determine the association of XRCC1 R399Q polymorphisms with CRC risk in the Chinese Han population.
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