Publications by authors named "Kai-Wen Duan"
Background: The efficacy of highly active antiretroviral therapy (HAART) can be estimated by the immunological response and the incidence of opportunistic infections.
Objective: This study aimed at evaluating the effectiveness of different durations of HAART in terms of immunological response markers (CD4 count and CD4/CD8 ratio) along with disease progression markers (incidence of oral lesions) in Chinese patients with HIV.
Methods: This single-center, retrospective, and real-world study included patients with HIV, grouped into a treatment group and treatment-naïve group, of which the former was further divided into 6, 12, and 18 months based on the treatment duration.
[Incidence of oral hairy leukoplakia in human immunodeficiency virus-seropositive adult patients in Yunnan, China].
Hua Xi Kou Qiang Yi Xue Za Zhi
April 2011
Article Synopsis
- The study aimed to investigate the rates and characteristics of oral hairy leukoplakia (OHL) in HIV-infected adults in Yunan, China, focusing on immune status.
- During the research period, 1,060 patients were evaluated, revealing that 8.9% had OHL, primarily affecting those with low CD4 lymphocyte counts.
- The findings suggest that OHL is common among severely immunocompromised HIV patients, indicating a relationship between reduced immune function and the presence of OHL.