Publications by authors named "Kai-Qing Wang"
Phytomedicine
December 2024
Article Synopsis
- Immune checkpoint blockade therapies, like PD-1 monoclonal antibodies, have shown promise in cancer treatment but struggle with colorectal cancer (CRC), leading researchers to explore new combination strategies, including traditional Chinese medicines.
- The study investigated the effects of Euphorbia Pekinensis extract (EP) on CRC through various laboratory methods and animal models, assessing its potential to enhance PD-1 blockade efficacy.
- Results revealed that EP contains key compounds, primarily diterpenoids and flavonoids, and effectively inhibited CRC cell growth by activating immune responses, suggesting it could improve treatment outcomes when combined with PD-1 therapy.
