Publications by authors named "Kai-Ning Shih"
Eur J Med Chem
April 2012
Article Synopsis
- A series of disubstituted 1,8-diamidoanthraquinones were created and tested for their ability to inhibit cell growth, telomerase activity, and hTERT expression.
- All compounds except 3a and 3s were chosen for further study by the NCI screening system.
- Notably, compounds 4e and 4k showed an ability to inhibit telomerase activity, suggesting that their effects on cell toxicity and telomerase inhibition could help in developing strategies that target telomerase.
