Publications by authors named "Kai-Kai Han"
2'-5'-Oligoadenylate synthetase-like protein (OASL) is an interferon-inducible antiviral protein that exerts antiviral effects through the RNase L- or retinoic acid-inducible gene I (RIG-I)-dependent signalling pathway. In this study, we identified and cloned the OASL gene (named duOASL) from healthy adult Cherry Valley ducks. Full-length duOASL cDNA (1630bp) encoded a 504-amino acid polypeptide containing three conserved domains, namely, nucleotidyltransferase domain, 2'-5'-oligoadenylate synthetase domain, and two ubiquitin-like repeats.
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- The H7N9 influenza A virus, first identified in humans in 2013, has spread among birds in China and poses a potential risk for public health.
- A survey conducted in April 2013 revealed 22 isolates of various influenza A viruses from live poultry markets and backyard farms, indicating a strong presence of H7N9 and related strains in the Yangtze Delta region.
- The findings suggest that improved biosecurity measures and better vaccination strategies are necessary for both backyard poultry farms and live poultry markets to mitigate the risk of viral transmission.