Publications by authors named "Kai-Ge Zhang"
Background: Over recent years, an increasing body of literature has focused on the relationship between erectile dysfunction (ED) and migraine. However, the specific mechanism is unclear.
Materials And Methods: We used a bioinformatic database to predict the targets and pathways associated with migraine and ED.
Objective: To study the therapeutic effect of Huoxue Tongluo Decoction (HXTLD) on erectile dysfunction caused by ischemic stroke and identify the mechanisms involved.
Methods: Network pharmacology was used to predict the key active ingredients and targets of HXTLD. Surgical methods were used to create a rat model of ischemic stroke.
Article Synopsis
- - The enzyme Carboxylesterase (CarE), specifically the CarE001G variant found in Helicoverpa armigera, plays a crucial role in detoxifying pesticides like β-cypermethrin, commonly used to control lepidopteran pests.
- - Researchers created four mutant versions of CarE001G with deletions in a specific glycine-rich region, finding that these variants exhibited increased metabolic efficiency against α-naphthyl acetate and enhanced activity against β-cypermethrin.
- - The study concludes that mutations in the glycine-rich region can qualitatively alter CarE's ability to detoxify β-cypermethrin, potentially leading to resistance in H. armigera in the future
Background: In China, although quite a few bold programmes have been made for HIV/AIDS, the epidemic has still shown an increasing trend.
Objectives: The study was aimed to investigate the characteristics of new HIV/AIDS and the major factors of false positives (FP) for HIV testing.
Methods: A retrospective review was performed in a teaching hospital in Xi'an between 2013 and 2018.